Mesothelioma Clinical Trials

Mesothelioma clinical trials can offer patients and their families hope if other treatments aren’t working. By joining a trial, you could access cutting-edge treatments and contribute to mesothelioma cancer research and the quest for a cure. Our team can help you find clinical trials for mesothelioma near you right now.

Medically reviewed by: Mark Levin, MD

Last updated:

What Are Clinical Trials for Mesothelioma?

Mesothelioma clinical trials are research studies that test new treatments, procedures, or combinations of therapies for this cancer.

These trials are conducted at top cancer centers across the U.S. and are key in advancing medical knowledge and finding better ways to treat mesothelioma.

Participating in a clinical trial may open the door to new cancer treatments that could help you live longer and manage symptoms more effectively.

“I’ve been in five different clinical trials since I was diagnosed with peritoneal mesothelioma, a rare cancer that develops in the lining of the abdominal cavity. Each clinical trial has extended my life a bit longer.”
– Dana, mesothelioma patient

Types of Mesothelioma Clinical Trials

Clinical trials are designed with various goals in mind. Learn more about the most common types of mesothelioma clinical trials below.

  • Prevention trials explore new ways of keeping mesothelioma from developing or returning.
  • Screening trials focus on improving or developing methods to detect mesothelioma before symptoms appear.
  • Diagnostic trials evaluate new tests to help detect mesothelioma earlier in patients who are already showing symptoms.
  • Treatment trials test innovative therapies and updated approaches to surgery, chemotherapy, and other standard treatments.
  • Quality-of-life trials aim to find better ways to manage mesothelioma symptoms and reduce treatment side effects.

If you’re interested in accessing new treatments through clinical trials, the first step is to find a doctor who specializes in mesothelioma.

Use our Free Doctor Match service for help connecting with local mesothelioma specialists.

Get Matched With a Mesothelioma Doctor
  • Find top specialists near you
  • Seek compensation for travel & care
  • Get medical guidance

Get Matched Now

Get Matched With a Mesothelioma Doctor

Find Mesothelioma Clinical Trials Near You

Use the dropdown menu below to find active mesothelioma clinical trials in your state.

Active Mesothelioma Clinical Trials (61)Show trials only in:
Clinical Trial for Triple Negative Breast Cancer from A&G Pharmaceutical Inc.
Location: Baltimore, Maryland
Call (866) 608-8933 to get help enrolling in this clinical trial
Clinical Trial for Triple Negative Breast Cancer from A&G Pharmaceutical Inc.

Our Patient Advocates can help you connect with clinical trials

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Trial Name
FIH Phase 1A /1B Study of AG01 Antibody Against Progranulin/GP88 in Advanced Solid Tumor Malignancies With Expansion Cohorts in Advanced Triple Negative Breast Ca, Hormone Resistant Breast Ca, Non Small Cell Lung Cancer and Mesothelioma

Conditions
  • Non Small Cell Lung Cancer
  • Mesothelioma
Interventions
  • Drug: AG-01 Compound
Facility
  • University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, Maryland
Clinical Trial for Advanced Solid Tumor from Constellation Pharmaceuticals
Location: Atlanta, Georgia (multiple locations)
Call (866) 608-8933 to get help enrolling in this clinical trial
Clinical Trial for Advanced Solid Tumor from Constellation Pharmaceuticals

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Trial Name
A Phase 1/2 Study of CPI-0209 in Patients With Advanced Solid Tumors and Lymphomas

Conditions
  • Mesothelioma, Malignant
Interventions
  • Drug: CPI-0209
Facility
  • Winship Cancer Institute of Emory University, Atlanta, Georgia
  • University of Chicago Medical Center, Chicago, Illinois
  • University of Maryland - Marlene and Stewart Greenebaum Cancer Center, Baltimore, Maryland
  • Massachusetts General Hospital, Boston, Massachusetts
  • Dana Farber Cancer Institute, Boston, Massachusetts
  • University of Michigan Hospital, Ann Arbor, Michigan
  • South Texas Accelerated Research Therapeutics (Start) - Midwest Location, Grand Rapids, Michigan
  • Hackensack University Medical Center, Hackensack, New Jersey
  • Montefiore Einstein Center for Cancer Care, Bronx, New York
  • NYU Langone Medical Center - Laura and Isaac Perlmutter Cancer Center, New York, New York
  • Weill Medical College of Cornell University, New York, New York
  • University of Cincinnati Medical Center, Cincinnati, Ohio
  • South Texas Accelerated Research Therapeutics, San Antonio, Texas
  • University of Virginia Health System, Charlottesville, Virginia
  • Swedish Cancer Institute, Seattle, Washington
  • Fred Hutchinson Cancer, Seattle, Washington
Clinical Trial for Pleural Biphasic Mesothelioma from Alliance for Clinical Trials in Oncology
Location: Anchorage, Alaska (multiple locations)
Call (866) 608-8933 to get help enrolling in this clinical trial
Clinical Trial for Pleural Biphasic Mesothelioma from Alliance for Clinical Trials in Oncology

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Trial Name
Official Title Neoadjuvant Immunotherapy in Sarcomatoid Mesothelioma

Conditions
  • Pleural Biphasic Mesothelioma
Interventions
  • Biological: Nivolumab
  • Biological: Ipilimumab
  • Procedure: Surgical Procedure
  • Procedure: Computed Tomography
  • Procedure: Magnetic Resonance Imaging
  • Procedure: Positron Emission Tomography
Facility
  • Anchorage Associates in Radiation Medicine, Anchorage, Alaska
  • Anchorage Radiation Therapy Center, Anchorage, Alaska
  • Alaska Breast Care and Surgery LLC, Anchorage, Alaska
  • Alaska Oncology and Hematology LLC, Anchorage, Alaska
  • Alaska Women's Cancer Care, Anchorage, Alaska
  • Katmai Oncology Group, Anchorage, Alaska
  • Providence Alaska Medical Center, Anchorage, Alaska
  • Kingman Regional Medical Center, Kingman, Arizona
  • Mayo Clinic Hospital in Arizona, Phoenix, Arizona
  • Mayo Clinic in Arizona, Scottsdale, Arizona
  • PCR Oncology, Arroyo Grande, California
  • Providence Saint Joseph Medical Center/Disney Family Cancer Center, Burbank, California
  • Providence Queen of The Valley, Napa, California
  • Providence Medical Foundation - Santa Rosa, Santa Rosa, California
  • Providence Santa Rosa Memorial Hospital, Santa Rosa, California
  • Beebe Medical Center, Lewes, Delaware
  • Beebe South Coastal Health Campus, Millville, Delaware
  • Delaware Clinical and Laboratory Physicians PA, Newark, Delaware
  • Helen F Graham Cancer Center, Newark, Delaware
  • Medical Oncology Hematology Consultants PA, Newark, Delaware
  • Christiana Care Health System-Christiana Hospital, Newark, Delaware
  • Beebe Health Campus, Rehoboth Beach, Delaware
  • Christiana Care Health System-Wilmington Hospital, Wilmington, Delaware
  • Mayo Clinic in Florida, Jacksonville, Florida
  • Saint Luke's Cancer Institute - Boise, Boise, Idaho
  • Saint Luke's Cancer Institute - Fruitland, Fruitland, Idaho
  • Saint Luke's Cancer Institute - Meridian, Meridian, Idaho
  • Saint Luke's Cancer Institute - Nampa, Nampa, Idaho
  • Saint Luke's Cancer Institute - Twin Falls, Twin Falls, Idaho
  • Rush - Copley Medical Center, Aurora, Illinois
  • Northwestern University, Chicago, Illinois
  • University of Chicago Comprehensive Cancer Center, Chicago, Illinois
  • Carle at The Riverfront, Danville, Illinois
  • Northwestern Medicine Cancer Center Kishwaukee, DeKalb, Illinois
  • Carle Physician Group-Effingham, Effingham, Illinois
  • Northwestern Medicine Cancer Center Delnor, Geneva, Illinois
  • Northwestern Medicine Glenview Outpatient Center, Glenview, Illinois
  • Northwestern Medicine Grayslake Outpatient Center, Grayslake, Illinois
  • Northwestern Medicine Lake Forest Hospital, Lake Forest, Illinois
  • Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois
  • Northwestern Medicine Orland Park, Orland Park, Illinois
  • Carle Cancer Center, Urbana, Illinois
  • Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois
  • Rush-Copley Healthcare Center, Yorkville, Illinois
  • Christiana Care - Union Hospital, Elkton, Maryland
  • Mayo Clinic in Rochester, Rochester, Minnesota
  • Saint Patrick Hospital - Community Hospital, Missoula, Montana
  • Carson Tahoe Regional Medical Center, Carson City, Nevada
  • Cancer and Blood Specialists-Henderson, Henderson, Nevada
  • Comprehensive Cancer Centers of Nevada - Henderson, Henderson, Nevada
  • Comprehensive Cancer Centers of Nevada-Horizon Ridge, Henderson, Nevada
  • Las Vegas Cancer Center-Henderson, Henderson, Nevada
  • OptumCare Cancer Care at Seven Hills, Henderson, Nevada
  • Comprehensive Cancer Centers of Nevada-Southeast Henderson, Henderson, Nevada
  • GenesisCare USA - Henderson, Henderson, Nevada
  • Las Vegas Urology - Green Valley, Henderson, Nevada
  • Las Vegas Urology - Pebble, Henderson, Nevada
  • Urology Specialists of Nevada - Green Valley, Henderson, Nevada
  • Las Vegas Urology - Pecos, Las Vegas, Nevada
  • OptumCare Cancer Care at Charleston, Las Vegas, Nevada
  • University Medical Center of Southern Nevada, Las Vegas, Nevada
  • Hope Cancer Care of Nevada, Las Vegas, Nevada
  • Radiation Oncology Centers of Nevada Central, Las Vegas, Nevada
  • Urology Specialists of Nevada - Central, Las Vegas, Nevada
  • GenesisCare USA - Las Vegas, Las Vegas, Nevada
  • Sunrise Hospital and Medical Center, Las Vegas, Nevada
  • Las Vegas Prostate Cancer Center, Las Vegas, Nevada
  • Las Vegas Urology - Sunset, Las Vegas, Nevada
  • Urology Specialists of Nevada - Southwest, Las Vegas, Nevada
  • Radiation Oncology Centers of Nevada Southeast, Las Vegas, Nevada
  • Ann M Wierman MD LTD, Las Vegas, Nevada
  • Comprehensive Cancer Centers of Nevada - Northwest, Las Vegas, Nevada
  • GenesisCare USA - Vegas Tenaya, Las Vegas, Nevada
  • Las Vegas Urology - Cathedral Rock, Las Vegas, Nevada
  • Las Vegas Urology - Smoke Ranch, Las Vegas, Nevada
  • OptumCare Cancer Care at MountainView, Las Vegas, Nevada
  • Urology Specialists of Nevada - Northwest, Las Vegas, Nevada
  • Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas, Nevada
  • Comprehensive Cancer Centers of Nevada - Town Center, Las Vegas, Nevada
  • Comprehensive Cancer Centers of Nevada-Summerlin, Las Vegas, Nevada
  • Summerlin Hospital Medical Center, Las Vegas, Nevada
  • Las Vegas Cancer Center-Medical Center, Las Vegas, Nevada
  • Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada
  • GenesisCare USA - Fort Apache, Las Vegas, Nevada
  • OptumCare Cancer Care at Fort Apache, Las Vegas, Nevada
  • Comprehensive Cancer Centers of Nevada - Central Valley, Las Vegas, Nevada
  • University Cancer Center, Las Vegas, Nevada
  • Hope Cancer Care of Nevada-Pahrump, Pahrump, Nevada
  • Renown Regional Medical Center, Reno, Nevada
  • Saint Mary's Regional Medical Center, Reno, Nevada
  • Radiation Oncology Associates, Reno, Nevada
  • Duke University Medical Center, Durham, North Carolina
  • Saint Charles Health System, Bend, Oregon
  • Clackamas Radiation Oncology Center, Clackamas, Oregon
  • Providence Cancer Institute Clackamas Clinic, Clackamas, Oregon
  • Bay Area Hospital, Coos Bay, Oregon
  • Providence Newberg Medical Center, Newberg, Oregon
  • Providence Willamette Falls Medical Center, Oregon City, Oregon
  • Providence Portland Medical Center, Portland, Oregon
  • Providence Saint Vincent Medical Center, Portland, Oregon
  • Saint Charles Health System-Redmond, Redmond, Oregon
  • Christiana Care Health System-Concord Health Center, Chadds Ford, Pennsylvania
  • Providence Regional Cancer System-Aberdeen, Aberdeen, Washington
  • Overlake Medical Center, Bellevue, Washington
  • PeaceHealth Saint Joseph Medical Center, Bellingham, Washington
  • Providence Regional Cancer System-Centralia, Centralia, Washington
  • Swedish Cancer Institute-Edmonds, Edmonds, Washington
  • Providence Regional Cancer Partnership, Everett, Washington
  • Swedish Cancer Institute-Issaquah, Issaquah, Washington
  • Kadlec Clinic Hematology and Oncology, Kennewick, Washington
  • Providence Regional Cancer System-Lacey, Lacey, Washington
  • PeaceHealth Saint John Medical Center, Longview, Washington
  • Skagit Regional Health Cancer Care Center, Mount Vernon, Washington
  • Valley Medical Center, Renton, Washington
  • Swedish Medical Center-Ballard Campus, Seattle, Washington
  • Swedish Medical Center-Cherry Hill, Seattle, Washington
  • Swedish Medical Center-First Hill, Seattle, Washington
  • PeaceHealth United General Medical Center, Sedro-Woolley, Washington
  • Providence Regional Cancer System-Shelton, Shelton, Washington
  • PeaceHealth Southwest Medical Center, Vancouver, Washington
  • Providence Saint Mary Regional Cancer Center, Walla Walla, Washington
  • North Star Lodge Cancer Center at Yakima Valley Memorial Hospital, Yakima, Washington
  • Providence Regional Cancer System-Yelm, Yelm, Washington
Clinical Trial for Ovarian Cancer, Epithelial from Nurix Therapeutics, Inc.
Location: Los Angeles, California (multiple locations)
Call (866) 608-8933 to get help enrolling in this clinical trial
Clinical Trial for Ovarian Cancer, Epithelial from Nurix Therapeutics, Inc.

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Call (866) 608-8933 to get started

Trial Name
A Phase 1a, Dose Escalation, Safety and Tolerability Study of NX-1607, a Casitas B-lineage Lymphoma Proto-oncogene (CBL-B) Inhibitor, in Adults With Advanced Malignancies, With Phase 1b Expansion in Select Tumor Types

Conditions
  • Malignant Pleural Mesothelioma (MPM)
Interventions
  • Drug: NX-1607
Facility
  • University of Southern California, Los Angeles, California
  • University of California, San Francisco, San Francisco, California
  • University of Colorado School of Medicine, Aurora, Colorado
  • University of Chicago, Chicago, Illinois
  • University of North Carolina, Chapel Hill, North Carolina
  • University of Oklahoma, Oklahoma City, Oklahoma
  • MD Anderson Cancer Center, Houston, Texas
  • University of Virginia, Charlottesville, Virginia
  • Swedish Cancer Institute, Seattle, Washington
  • Fred Hutchinson Cancer Center, Seattle, Washington
Clinical Trial for Ovarian Cancer from Verismo Therapeutics
Location: Westwood, Kansas (multiple locations)
Call (866) 608-8933 to get help enrolling in this clinical trial
Clinical Trial for Ovarian Cancer from Verismo Therapeutics

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Trial Name
A Phase 1 Study of SynKIR-110, Autologous T Cells Transduced with Mesothelin KIR-CAR, in Subjects with Mesothelin-Expressing Advanced Ovarian Cancer, Cholangiocarcinoma, or Mesothelioma

Conditions
  • Mesothelioma, Malignant
Interventions
  • Biological: SynKIR-110, Autologous T cells Transduced with Mesothelin KIR-CAR
Facility
  • University of Kansas Cancer Center, Westwood, Kansas
  • University of Pennsylvania, Philadelphia, Pennsylvania
  • MD Anderson Cancer Center, Houston, Texas
  • University of Wisconsin Carbone Cancer Center, Madison, Wisconsin
Clinical Trial for Peritoneal Malignant Mesothelioma from National Cancer Institute (NCI)
Location: Phoenix, Arizona (multiple locations)
Call (866) 608-8933 to get help enrolling in this clinical trial
Clinical Trial for Peritoneal Malignant Mesothelioma from National Cancer Institute (NCI)

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Call (866) 608-8933 to get started

Trial Name
Phase 2 Randomized Trial of Neoadjuvant or Palliative Chemotherapy With or Without Immunotherapy for Peritoneal Mesothelioma

Conditions
  • Peritoneal Malignant Mesothelioma
Interventions
  • Biological: Atezolizumab
  • Biological: Bevacizumab
  • Procedure: Biospecimen Collection
  • Drug: Carboplatin
  • Procedure: Computed Tomography
  • Procedure: Cytoreductive Surgery
  • Drug: Hyperthermic Intraperitoneal Chemotherapy
  • Drug: Pemetrexed
  • Procedure: Positron Emission Tomography
Facility
  • Mayo Clinic Hospital in Arizona, Phoenix, Arizona
  • University of Chicago Comprehensive Cancer Center, Chicago, Illinois
  • Carle at The Riverfront, Danville, Illinois
  • Carle Physician Group-Effingham, Effingham, Illinois
  • Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois
  • Carle Cancer Center, Urbana, Illinois
  • The Carle Foundation Hospital, Urbana, Illinois
  • University of Kentucky/Markey Cancer Center, Lexington, Kentucky
  • Alliance for Clinical Trials in Oncology, Boston, Massachusetts
  • Sanford Joe Lueken Cancer Center, Bemidji, Minnesota
  • Mercy Hospital, Coon Rapids, Minnesota
  • Fairview Southdale Hospital, Edina, Minnesota
  • Unity Hospital, Fridley, Minnesota
  • Abbott-Northwestern Hospital, Minneapolis, Minnesota
  • Mayo Clinic in Rochester, Rochester, Minnesota
  • Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota
  • Regions Hospital, Saint Paul, Minnesota
  • United Hospital, Saint Paul, Minnesota
  • Sanford Cancer Center Worthington, Worthington, Minnesota
  • Sanford Bismarck Medical Center, Bismarck, North Dakota
  • Sanford Broadway Medical Center, Fargo, North Dakota
  • Sanford Roger Maris Cancer Center, Fargo, North Dakota
  • Ohio State University Comprehensive Cancer Center, Columbus, Ohio
  • University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
  • University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania
  • Sanford Cancer Center Oncology Clinic, Sioux Falls, South Dakota
  • Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota
  • MD Anderson in The Woodlands, Conroe, Texas
  • M D Anderson Cancer Center, Houston, Texas
  • MD Anderson West Houston, Houston, Texas
  • MD Anderson League City, League City, Texas
  • MD Anderson in Sugar Land, Sugar Land, Texas
  • ThedaCare Regional Cancer Center, Appleton, Wisconsin
  • Marshfield Medical Center-EC Cancer Center, Eau Claire, Wisconsin
  • Marshfield Medical Center-Marshfield, Marshfield, Wisconsin
  • Marshfield Medical Center - Minocqua, Minocqua, Wisconsin
  • Marshfield Medical Center-Rice Lake, Rice Lake, Wisconsin
  • Marshfield Medical Center-River Region at Stevens Point, Stevens Point, Wisconsin
  • Marshfield Medical Center - Weston, Weston, Wisconsin
Clinical Trial for Pulmonary Edema from Brigham and Women's Hospital
Location: Boston, Massachusetts
Call (866) 608-8933 to get help enrolling in this clinical trial
Clinical Trial for Pulmonary Edema from Brigham and Women's Hospital

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Trial Name
Clinical Utility of Portable Dynamic Chest X-Ray (DDR) in the ICU: Clinical Trial to Demonstrate the Feasibility of Deploying DDR Technology in the ICU - A Study to Prove Its Increased Diagnostic Value

Conditions
  • Mesothelioma
Interventions
  • Diagnostic Test: Portable Dynamic Digital Radiography (DDR)
Facility
  • Brigham and Women's Hospital, Boston, Massachusetts
Clinical Trial for Mesothelioma from BridGene Biosciences Inc.
Location: Houston, Texas
Call (866) 608-8933 to get help enrolling in this clinical trial
Clinical Trial for Mesothelioma from BridGene Biosciences Inc.

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Trial Name
A Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of BGC515 Capsules in Patients With Advanced Solid Tumors

Conditions
  • Mesothelioma
Interventions
  • Drug: BGC515
Facility
  • MD Anderson Cancer Center, Houston, Texas
Clinical Trial for Mesothelioma from Dana-Farber Cancer Institute
Location: Boston, Massachusetts
Call (866) 608-8933 to get help enrolling in this clinical trial
Clinical Trial for Mesothelioma from Dana-Farber Cancer Institute

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Trial Name
Prospectively Collected Pleural Biopsies for Validation of Malignant Pleural Mesothelioma Prognostic Biomarkers

Conditions
  • Mesothelioma
Interventions
  • Other: MPT Test
  • Other: CLDN15/VIM Test
Facility
  • Brigham and Women's Hospital, Boston, Massachusetts
Clinical Trial for Mesothelioma from National Institutes of Health Clinical Center (CC)
Location: Bethesda, Maryland
Call (866) 608-8933 to get help enrolling in this clinical trial
Clinical Trial for Mesothelioma from National Institutes of Health Clinical Center (CC)

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Trial Name
Long Term Follow-up of Mesothelioma Patients and Their Family Members With Germline Mutations in BAP1 and Other Genes

Conditions
  • Mesothelioma
Facility
  • National Institutes of Health Clinical Center, Bethesda, Maryland
Clinical Trial for Advanced Solid Tumor from Medicenna Therapeutics, Inc.
Location: San Francisco, California (multiple locations)
Call (866) 608-8933 to get help enrolling in this clinical trial
Clinical Trial for Advanced Solid Tumor from Medicenna Therapeutics, Inc.

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Trial Name
A Phase 1/2 Open Label, Dose Escalation and Expansion Study of MDNA11, IL-2 Superkine, Administered Alone or in Combination With Immune Checkpoint Inhibitor in Patients With Advanced Solid Tumors

Conditions
  • Non-Small Cell Lung Cancer Squamous
  • Non-Small Cell Lung Cancer Non-squamous
  • Pleural Mesothelioma
Interventions
  • Drug: MDNA11
  • Drug: Pembrolizumab (KEYTRUDA®)
Facility
  • UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California
  • Providence Saint John's Health Center, Santa Monica, California
  • Boca Raton Regional Hospital, Boca Raton, Florida
  • Orlando Health Cancer Institute, Orlando, Florida
  • Emory - Winship Cancer Institute, Atlanta, Georgia
  • Karmanos Cancer Institute, Detroit, Michigan
  • MD Anderson Cancer Center, Houston, Texas
Clinical Trial for Locally Advanced Solid Tumor from Tango Therapeutics, Inc.
Location: Palo Alto, California (multiple locations)
Call (866) 608-8933 to get help enrolling in this clinical trial
Clinical Trial for Locally Advanced Solid Tumor from Tango Therapeutics, Inc.

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Trial Name
A Phase 1/2, Multi-Center, Open-Label Study to Evaluate the Safety, Tolerability, and Preliminary Anti-tumor Activity of TNG462 as a Single Agent and in Combination in Patients With MTAP-deleted Advanced or Metastatic Solid Tumors

Conditions
    Interventions
    • Drug: TNG462
    • Drug: Pembrolizumab
    Facility
    • Stanford University, Palo Alto, California
    • Grand Valley Oncology, Grand Junction, Colorado
    • Sylvester Comprehensive Cancer Center, Miami, Florida
    • University Chicago Medicine, Chicago, Illinois
    • Carle Cancer Center, Urbana, Illinois
    • Dana Farber Cancer Institute, Boston, Massachusetts
    • Henry Ford Cancer Center, Detroit, Michigan
    • New York University Langone Health, New York, New York
    • Sarah Cannon Tennessee Oncology, Nashville, Tennessee
    • The University of Texas MD Anderson Cancer Center, Houston, Texas
    • Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah
    • Next Oncology Virginia, Fairfax, Virginia
    Clinical Trial for Mesothelioma from National Institutes of Health Clinical Center (CC)
    Location: Bethesda, Maryland
    Call (866) 608-8933 to get help enrolling in this clinical trial
    Clinical Trial for Mesothelioma from National Institutes of Health Clinical Center (CC)

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    Trial Name
    Phase II Evaluation of Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma

    Conditions
    • Mesothelioma
    Interventions
    • Drug: Decitabine/cedazuridine
    Facility
    • National Institutes of Health Clinical Center, Bethesda, Maryland
    Clinical Trial for Malignant Pleural Mesotheliomas NOS from National Institutes of Health Clinical Center (CC)
    Location: Bethesda, Maryland
    Call (866) 608-8933 to get help enrolling in this clinical trial
    Clinical Trial for Malignant Pleural Mesotheliomas NOS from National Institutes of Health Clinical Center (CC)

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    Trial Name
    Prospective Evaluation of Genetic and Epigenetic Alterations in Patients With Thoracic Malignancies

    Conditions
    • Malignant Pleural Mesotheliomas NOS
    • Lung Cancer NOS
    • Thoracic Cancers
    Facility
    • National Institutes of Health Clinical Center, Bethesda, Maryland
    Clinical Trial for Carcinoma, Non-Small-Cell Lung from Novartis
    Location: Boston, Massachusetts (multiple locations)
    Call (866) 608-8933 to get help enrolling in this clinical trial
    Clinical Trial for Carcinoma, Non-Small-Cell Lung from Novartis

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    Trial Name
    A Phase I, Open-label, Multi-center Study of KFA115 as a Single Agent and in Combination With Pembrolizumab in Patients With Select Advanced Cancers

    Conditions
    • Mesothelioma
    Interventions
    • Drug: KFA115
    Facility
    • Massachusetts General Hospital ., Boston, Massachusetts
    • NYU School of Medicine, New York, New York
    • University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
    • SCRI Oncology Partners, Nashville, Tennessee
    Clinical Trial for Solid Tumor from Actym Therapeutics, Inc.
    Location: Los Angeles, California (multiple locations)
    Call (866) 608-8933 to get help enrolling in this clinical trial
    Clinical Trial for Solid Tumor from Actym Therapeutics, Inc.

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    Trial Name
    A Phase 1a/1b Open-label, Dose-Escalation and Expansion Study of ACTM-838 as a Single Agent in Patients With Advanced Solid Tumors

    Conditions
      Interventions
      • Drug: ACTM-838
      Facility
      • University of Southern California Norris Comprehensive Cancer Center, 1441 Eastlake Ave., Los Angeles, California
      • UPMC Hillman Cancer Center, 5115 Centre Ave, Pittsburgh, Pennsylvania
      Clinical Trial for Pleural Effusion, Malignant from Travera Inc
      Location: Oakland, California
      Call (866) 608-8933 to get help enrolling in this clinical trial
      Clinical Trial for Pleural Effusion, Malignant from Travera Inc

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      Trial Name
      Mass Response of Tumor Cells As a Biomarker for Rapid Therapy Guidance

      Conditions
      • Pleural Effusion, Malignant
      • Ascites, Malignant
      • Mesothelioma
      Facility
      • xCures, Oakland, California
      Clinical Trial for CD30-Positive Neoplastic Cells Present from M.D. Anderson Cancer Center
      Location: Houston, Texas
      Call (866) 608-8933 to get help enrolling in this clinical trial
      Clinical Trial for CD30-Positive Neoplastic Cells Present from M.D. Anderson Cancer Center

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      Trial Name
      Phase II Trial of Adcetris (Brentuximab Vedotin) in CD30+ Malignant Mesothelioma

      Conditions
      • Malignant Mesothelioma
      Interventions
      • Drug: Brentuximab Vedotin
      • Other: Laboratory Biomarker Analysis
      Facility
      • M D Anderson Cancer Center, Houston, Texas
      Clinical Trial for Malignant Pleural Mesothelioma from Memorial Sloan Kettering Cancer Center
      Location: Basking Ridge, New Jersey (multiple locations)
      Call (866) 608-8933 to get help enrolling in this clinical trial
      Clinical Trial for Malignant Pleural Mesothelioma from Memorial Sloan Kettering Cancer Center

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      Trial Name
      Phase I Dose Escalation and Local Control Study of Pembrolizumab + Intensity-Modulated Pleural Radiation Therapy (IMPRINT) for Malignant Pleural Mesothelioma

      Conditions
      • Malignant Pleural Mesothelioma
      Interventions
      • Drug: Pembrolizumab
      • Radiation: IMPRINT
      Facility
      • Memorial Sloan Kettering Basking Ridge (Limited protocol activities), Basking Ridge, New Jersey
      • Memorial Sloan Kettering Monmouth (Limited Protocol Activities), Middletown, New Jersey
      • Memorial Sloan Kettering Bergen (Limited Protocol Activities), Montvale, New Jersey
      • Memorial Sloan Kettering Suffolk- Commack (Limited Protocol Activities), Commack, New York
      • Memorial Sloan Kettering Westchester (Limited Protocol Activities), Harrison, New York
      • Memorial Sloan Kettering Cancer Center, New York, New York
      • Memorial Sloan Kettering Nassau (Limited protocol activities), Rockville Centre, New York
      Clinical Trial for Platinum-Resistant Ovarian Cancer from Genmab
      Location: Phoenix, Arizona (multiple locations)
      Call (866) 608-8933 to get help enrolling in this clinical trial
      Clinical Trial for Platinum-Resistant Ovarian Cancer from Genmab

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      Trial Name
      Phase 1/2 Study of Rina-S in Patients With Locally Advanced and/or Metastatic Solid Tumors

      Conditions
      • Primary Peritoneal Carcinoma
      • Non-small Cell Lung Cancer
      • Mesothelioma
      Interventions
      • Drug: Rina-S
      Facility
      • USOR HonorHealth, Phoenix, Arizona
      • USOR Arizona Oncology Associates, Tucson, Arizona
      • University of California Los Angeles Medical Center 106, Los Angeles, California
      • University of California, San Diego; Moores Cancer Center, San Diego, California
      • USOR Sansum Clinic, Santa Barbara, California
      • Providence Medical Foundation, Santa Rosa, California
      • USOR Florida Cancer Specialists South, Fort Myers, Florida
      • USOR Florida Cancer Specialists North, Saint Petersburg, Florida
      • USOR Florida Cancer Specialists East, West Palm Beach, Florida
      • University of Kansas Medical Center (KUMC), Westwood, Kansas
      • USOR Maryland Oncology Hematology, Rockville, Maryland
      • Massachusetts General Hospital, Boston, Massachusetts
      • Dana Farber Cancer Institute, Boston, Massachusetts
      • Karmanos Cancer Institute, Detroit, Michigan
      • START Midwest, Grand Rapids, Michigan
      • USOR Minnesota Oncology Hematology, Maplewood, Minnesota
      • University of Oklahoma - Health Sciences Center, Oklahoma City, Oklahoma
      • USOR Oncology Associates of Oregon, P.C., Eugene, Oregon
      • Compass Oncology - Rose Quarter, Portland, Oregon
      • Compass Oncology- Rose Quarter, Portland, Oregon
      • USOR Alliance Cancer Specialist, Doylestown, Pennsylvania
      • Women and Infants Hospital of Rhode Island, Providence, Rhode Island
      • Sarah Cannon Research Institute at Tennessee Oncology, Nashville, Tennessee
      • USOR Texas Oncology, Abilene, Texas
      • Texas Oncology - Central / South Texas, Austin, Texas
      • Texas Oncology- Central/South Texas, Austin, Texas
      • Mary Crowley Cancer Research, Dallas, Texas
      • USOR Texas Oncology, Fort Worth, Texas
      • Texas Oncology - Northeast TX, Tyler, Texas
      • Texas Oncology-Northeast TX, Tyler, Texas
      • USOR Texas Oncology Gulf Coast, Woodland, Texas
      • START Mountain Region, West Valley City, Utah
      • USOR Virginia Cancer Specialists, Fairfax, Virginia
      • USOR Virginia Oncology Associates, Norfolk, Virginia
      Clinical Trial for Cutaneous Melanoma from Seagen Inc.
      Location: Phoenix, Arizona (multiple locations)
      Call (866) 608-8933 to get help enrolling in this clinical trial
      Clinical Trial for Cutaneous Melanoma from Seagen Inc.

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      Trial Name
      A Phase 1 Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors

      Conditions
      • Non-small Cell Lung Cancer
      • Mesothelioma
      Interventions
      • Drug: PF-08046049
      Facility
      • Mayo Clinic Arizona, Phoenix, Arizona
      • UCLA Hematology/Oncology - Administrative Office, Los Angeles, California
      • The Angeles Clinic and Research Institute, Los Angeles, California
      • Cedars-Sinai Medical Center, Los Angeles, California
      • Ronald Reagan UCLA Medical Center, Drug Information Center, Los Angeles, California
      • UCLA Hematology/Oncology, Los Angeles, California
      • University of California Los Angeles Medical Center, Los Angeles, California
      • UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California
      • UCSF Medical Center, Investigational Pharmacy, San Francisco, California
      • University of California, San Francisco | HDFCCC - Hematopoietic Malignancies, San Francisco, California
      • The Angeles Clinic and Research Institute, A Cedars-Sinai Affiliate (Emergency Back-up only), Santa Monica, California
      • Quest Diagnostics Incorporated - Denver, Denver, Colorado
      • Presbyterian St. Lukes Medical Center, Denver, Colorado
      • Sarah Cannon Research Institute at HealthONE - Denver, Denver, Colorado
      • Mayo Clinic Florida, Jacksonville, Florida
      • Northwestern Medical Group, Chicago, Illinois
      • Northwestern Memorial Hospital, Chicago, Illinois
      • Northwestern University, Chicago, Illinois
      • Massachusetts General Hospital, Boston, Massachusetts
      • Brigham and Women's Hospital Clinic Lab (285), Boston, Massachusetts
      • Dana-Farber Cancer Institute (DFCI), Boston, Massachusetts
      • Mayo Clinic Rochester, Rochester, Minnesota
      • Laboratory Corporation of America, Raritan, New Jersey
      • Laura & Isaac Perlmutter Cancer Center at NYU Langone Health, New York, New York
      • New York University (NYU) Cancer Institute, New York, New York
      • NYU Langone Medical Center(Tisch Hospital), New York, New York
      • Texas Oncology-Baylor Charles A. Sammons Cancer Center, Dallas, Texas
      • Texas Oncology - Baylor Sammons Cancer Center, Dallas, Texas
      • US Oncology Investigational Products Center (IPC), Irving, Texas
      • Fred Hutchinson Cancer Center / Seattle Cancer Care Alliance / University of Washington, Seattle, Washington
      • Fred Hutchinson Cancer Center, Seattle, Washington
      • University of Washington Medical Center, Seattle, Washington
      Clinical Trial for Mesothelioma from National Institutes of Health Clinical Center (CC)
      Location: Bethesda, Maryland
      Call (866) 608-8933 to get help enrolling in this clinical trial
      Clinical Trial for Mesothelioma from National Institutes of Health Clinical Center (CC)

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      Trial Name
      Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma and Other Mesothelin Expressing Cancers

      Conditions
      • Mesothelioma
      Facility
      • National Institutes of Health Clinical Center, Bethesda, Maryland
      Clinical Trial for Advanced Cancer from 7 Hills Pharma, LLC
      Location: Lake Mary, Florida (multiple locations)
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      Clinical Trial for Advanced Cancer from 7 Hills Pharma, LLC

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      Trial Name
      A Phase 1b/2a Multi-Center, Dose Escalation and Reference Regimen-Controlled, Multi-Cohort Study to Determine the Safety and Efficacy of Oral 7HP349 (Alintegimod) in Combination with Ipilimumab Followed by Nivolumab Monotherapy in Patients with Locally Advanced or Metastatic Cancers Following One or More Prior Therapies

      Conditions
      • Pleural Mesothelioma
      • Non Small Cell Lung Cancer
      Interventions
      • Drug: Alintegimod
      • Drug: Ipilimumab
      • Drug: Nivolumab
      Facility
      • Florida Cancer Specialists, Lake Mary, Florida
      • Dartmouth Hitchcock, Lebanon, New Hampshire
      • MD Anderson Cancer Center, Houston, Texas
      Clinical Trial for Mesothelioma from Novartis
      Location: Los Angeles, California (multiple locations)
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      Clinical Trial for Mesothelioma from Novartis

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      Trial Name
      An Open-label, Multi-center, Phase I Study of Oral IAG933 in Adult Patients With Advanced Mesothelioma and Other Solid Tumors

      Conditions
      • Mesothelioma
      Interventions
      • Drug: IAG933
      Facility
      • University of California LA, Los Angeles, California
      • Uni of Chi Medi Ctr Hema and Onco, Chicago, Illinois
      • Sidney Kimmel CCC At JH, Baltimore, Maryland
      • Massachusetts General Hospital Massachusetts General Hospital, Boston, Massachusetts
      • Cleveland Clinic Foundation, Cleveland, Ohio
      • MD Anderson Cancer Center, Houston, Texas
      Clinical Trial for Advanced Cancer from Merck Sharp & Dohme LLC
      Location: New Brunswick, New Jersey (multiple locations)
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      Clinical Trial for Advanced Cancer from Merck Sharp & Dohme LLC

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      Trial Name
      A Clinical Trial of Pembrolizumab (MK-3475) Evaluating Predictive Biomarkers in Subjects With Advanced Solid Tumors (KEYNOTE 158)

      Conditions
      • Small Cell Lung Carcinoma
      • Small Cell Lung Cancer (SCLC)
      • Mesothelioma
      Interventions
      • Biological: pembrolizumab
      Facility
      • Call for Information (Investigational Site 0008), New Brunswick, New Jersey
      Clinical Trial for Solid Tumours from Epkin
      Location: Beverly Hills, California (multiple locations)
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      Clinical Trial for Solid Tumours from Epkin

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      Trial Name
      A Phase 1, Open-label, Multicenter, Dose-escalation and Cohort Expansion Study of OKN4395, a Dual Antagonist of EP2 and EP4 Prostanoid Receptors, As Monotherapy and in Combination with Pembrolizumab, in Patients with Advanced Solid Tumours.

      Conditions
      • Malignant Mesothelioma
      • Non Small Cell Lung Cancer
      Interventions
      • Drug: OKN4395
      Facility
      • Precision NextGen Oncology and Research Center, Beverly Hills, California
      • Sarcoma Oncology Center, Santa Monica, California
      Clinical Trial for Mesothelioma from Brigham and Women's Hospital
      Location: Boston, Massachusetts
      Call (866) 608-8933 to get help enrolling in this clinical trial
      Clinical Trial for Mesothelioma from Brigham and Women's Hospital

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      Trial Name
      MAGIC-AKI: Magnesium for the Prevention of Hyperthermic Intraoperative Cisplatin-Associated AKI

      Conditions
      • Mesothelioma
      Interventions
      • Drug: Magnesium sulfate
      Facility
      • Brigham and Women's Hospital, Boston, Massachusetts
      Clinical Trial for Uveal Melanoma from Ohio State University
      Location: Columbus, Ohio
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      Clinical Trial for Uveal Melanoma from Ohio State University

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      Trial Name
      Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome

      Conditions
      • BAP1 Gene Mutation
      • Mesothelioma
      Facility
      • The Ohio State University Wexner Medical Center, Columbus, Ohio
      Clinical Trial for Malignant Peritoneal Mesothelioma from Memorial Sloan Kettering Cancer Center
      Location: Chicago, Illinois (multiple locations)
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      Clinical Trial for Malignant Peritoneal Mesothelioma from Memorial Sloan Kettering Cancer Center

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      Trial Name
      ICARuS II (Intraperitoneal Chemotherapy After cytoReductive Surgery): A Multicenter, Randomized Phase II Trial of Normothermic Intraperitoneal Chemotherapy and Intravenous Chemotherapy After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Malignant Peritoneal Mesothelioma

      Conditions
      • Peritoneal Mesothelioma
      • Mesothelioma
      • Mesothelioma, Malignant
      • Malignant Mesothelioma
      Interventions
      • Drug: Pemetrexed
      • Drug: Cisplatin
      • Drug: Carboplatin
      Facility
      • University of Chicago (Data Collection Only), Chicago, Illinois
      • University of Michigan (Data Collection Only), Ann Arbor, Michigan
      • Washington University (Data Collection Only), Saint Louis, Missouri
      • University of Nebraska (Data collection only), Omaha, Nebraska
      • Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities), Basking Ridge, New Jersey
      • Memorial Sloan Kettering Monmouth (Limited Protocol Activities), Middletown, New Jersey
      • Memorial Sloan Kettering Bergen (Limited Protocol Activities), Montvale, New Jersey
      • Rutgers University (Data Collection Only), New Brunswick, New Jersey
      • Memorial Sloan Kettering Commack (Limited Protocol Activities), Commack, New York
      • Memorial Sloan Kettering Westchester (Limited Protocol Activites), Harrison, New York
      • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York, New York
      • Memorial Sloan Kettering Nassau (Limited Protocol Activities), Uniondale, New York
      • Allegheny Health Network (Data Collection Only), Pittsburgh, Pennsylvania
      Clinical Trial for Peritoneal Carcinomatosis from National Institutes of Health Clinical Center (CC)
      Location: Bethesda, Maryland
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      Clinical Trial for Peritoneal Carcinomatosis from National Institutes of Health Clinical Center (CC)

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      Trial Name
      Individualized Response Assessment to Heated Intraperitoneal Chemotherapy (HIPEC) for the Treatment of Peritoneal Carcinomatosis From Ovarian, Colorectal, Appendiceal, or Peritoneal Mesothelioma Histologies

      Conditions
      • Peritoneal Carcinomatosis
      • Peritoneal Mesothelioma
      Interventions
      • Procedure: Heated Intraperitonial Chemotherapy
      • Drug: Oxaliplatin
      • Drug: 5-Fluorouracil
      Facility
      • National Institutes of Health Clinical Center, Bethesda, Maryland
      Clinical Trial for Mesothelin-Expressing Tumors from Context Therapeutics Inc.
      Location: San Antonio, Texas
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      Clinical Trial for Mesothelin-Expressing Tumors from Context Therapeutics Inc.

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      Trial Name
      Phase 1 Study of CT-95 in Advanced Cancers Associated with Mesothelin Expression

      Conditions
        Interventions
        • Drug: CT-95
        Facility
        • Context Investigational Site, San Antonio, Texas
        Clinical Trial for Recurrent Cutaneous Melanoma from M.D. Anderson Cancer Center
        Location: Houston, Texas
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        Clinical Trial for Recurrent Cutaneous Melanoma from M.D. Anderson Cancer Center

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        Trial Name
        Ex-Vivo Expanded Allogeneic NK Cells for the Treatment of Solid Tumors of Pediatric Origin in Children and Young Adults

        Conditions
        • Recurrent Malignant Mesothelioma
        • Refractory Malignant Mesothelioma
        Interventions
        • Biological: Cord Blood-derived Expanded Allogeneic Natural Killer Cells
        • Drug: Cyclophosphamide
        • Drug: Etoposide
        Facility
        • M D Anderson Cancer Center, Houston, Texas
        Clinical Trial for Familial Cancer from National Institutes of Health Clinical Center (CC)
        Location: Bethesda, Maryland
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        Clinical Trial for Familial Cancer from National Institutes of Health Clinical Center (CC)

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        Trial Name
        Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome

        Conditions
        • Mesothelioma
        Facility
        • National Institutes of Health Clinical Center, Bethesda, Maryland
        Clinical Trial for Ovarian Carcinoma from Numab Therapeutics AG
        Location: Birmingham, Alabama (multiple locations)
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        Clinical Trial for Ovarian Carcinoma from Numab Therapeutics AG

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        Trial Name
        A Phase 1 Study of NM32-2668 (Anti-ROR1/CD3/Anti-HSA Tri-Specific Antibody) in Adult Patients with Selected Advanced Solid Tumors

        Conditions
        • Peritoneal Carcinoma
        • Mesothelioma, Malignant
        Interventions
        • Biological: NM32-2668
        Facility
        • University of Alabama at Birmingham, Birmingham, Alabama
        • USC Norris Comprehensive Cancer Center, Los Angeles, California
        • Duke University, Durham, North Carolina
        • Cleveland Clinic, Cleveland, Ohio
        • University of Pittsburgh Medical Center (UPMC) - Hillman Cancer Center, Pittsburgh, Pennsylvania
        • Lifespan Cancer Institute at Rhode Island Hospital, Providence, Rhode Island
        • Medical University of South Carolina (MUSC), Charleston, South Carolina
        • Mary Crowley Cancer Research, Dallas, Texas
        Clinical Trial for Advanced Solid Tumors from PharmaMar
        Location: Santa Monica, California (multiple locations)
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        Clinical Trial for Advanced Solid Tumors from PharmaMar

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        Trial Name
        Phase I/II, Multicenter, Open-label, Clinical and Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Pretreated Patients With Selected Advanced Solid Tumors

        Conditions
        • Soft Tissue Sarcoma (Excluding GIST)
        • Mesothelioma
        Interventions
        • Drug: Lurbinectedin
        • Drug: Irinotecan
        Facility
        • Sarcoma Oncology Center, Santa Monica, California
        • Massachusetts General Hospital -, Boston, Massachusetts
        • Beth Israel Deaconess Medical Center, Boston, Massachusetts
        • The University of Texas MD Anderson Cancer Center, Houston, Texas
        Clinical Trial for Solid Tumor, Adult from A2 Biotherapeutics Inc.
        Location: Gilbert, Arizona (multiple locations)
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        Clinical Trial for Solid Tumor, Adult from A2 Biotherapeutics Inc.

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        Trial Name
        An Observational Study Obtaining Solid Tumor Tissue from Participants and Apheresis for CAR T-Cell Therapy Manufacturing

        Conditions
        • Non Small Cell Lung Cancer
        • Mesothelioma
        • Mesothelioma, Malignant
        • Mesothelioma; Lung
        Facility
        • Banner Health, Gilbert, Arizona
        • City of Hope, Duarte, California
        • University of California San Diego, La Jolla, California
        • Stanford University, Palo Alto, California
        • UCLA Medical Center, Santa Monica, California
        • Mayo Clinic Jacksonville, Jacksonville, Florida
        • Moffitt Cancer Center, Tampa, Florida
        • Massachusetts General Hospital/Dana Farber Cancer Institute, Boston, Massachusetts
        • Mayo Clinic Rochester, Rochester, Minnesota
        • Washington University, Saint Louis, Missouri
        • NYU Langone Medical Center, New York, New York
        • MD Anderson Cancer Center, Houston, Texas
        • Fred Hutchinson Cancer Center, Seattle, Washington
        Clinical Trial for Malignant Pleural Mesothelioma from Memorial Sloan Kettering Cancer Center
        Location: Basking Ridge, New Jersey (multiple locations)
        Call (866) 608-8933 to get help enrolling in this clinical trial
        Clinical Trial for Malignant Pleural Mesothelioma from Memorial Sloan Kettering Cancer Center

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        Trial Name
        Breathprinting (E-Nose) Technology to Measure Response to Treatment of Malignant Pleural Mesothelioma (MPM) Through MPM-Specific Volatile Organic Compounds Detected in Exhalates

        Conditions
        • Malignant Pleural Mesothelioma
        Interventions
        • Diagnostic Test: E-Nose testing
        • Diagnostic Test: Research blood
        Facility
        • Memorial Sloan Kettering Basking Ridge (Consent Only), Basking Ridge, New Jersey
        • Memorial Sloan Kettering Monmouth (Consent Only), Middletown, New Jersey
        • Memorial Sloan Kettering Bergen (Consent Only ), Montvale, New Jersey
        • Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (Consent Only), Commack, New York
        • Memorial Sloan Kettering Westchester (Consent Only), Harrison, New York
        • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York, New York
        • Memorial Sloan Kettering Nassau (Consent Only), Uniondale, New York
        Clinical Trial for Malignant Mesothelioma from InSilico Medicine Hong Kong Limited
        Location: Denver, Colorado (multiple locations)
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        Clinical Trial for Malignant Mesothelioma from InSilico Medicine Hong Kong Limited

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        Trial Name
        A Phase 1, Open-Label, Multicenter, FIH Study to Evaluate the Safety, Tolerability, Pharmacokinetics/Pharmacodynamics, and Preliminary Efficacy of ISM6331 in Participants With Advanced/Metastatic Malignant Mesothelioma or Other Solid Tumors

        Conditions
        • Malignant Mesothelioma
        Interventions
        • Drug: ISM6331
        Facility
        • Sarah Cannon Research Institute at HealthONE, Denver, Colorado
        • University Hospitals Cleveland Medical Center, Cleveland, Ohio
        • SCRI Oncology Partners, Nashville, Tennessee
        Clinical Trial for Gastric Cancers from University of Chicago
        Location: Chicago, Illinois
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        Clinical Trial for Gastric Cancers from University of Chicago

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        Trial Name
        Tissue Procurement for Gastric Cancer, Gastrointestinal Stromal Tumors (GIST), Esophageal Cancer, Pancreas Cancer, Hepatocellular Cancer, Biliary Cancer, Neuroendocrine, Peritoneal Mesothelioma, Anal Cancer and Colorectal Cancer in Patients Undergoing Surgery or Biopsy

        Conditions
          Facility
          • The University of Chicago, Chicago, Illinois
          Clinical Trial for Clear Cell Renal Cell Carcinoma from CRISPR Therapeutics
          Location: Duarte, California (multiple locations)
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          Clinical Trial for Clear Cell Renal Cell Carcinoma from CRISPR Therapeutics

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          Trial Name
          A Phase 1/2, Open-label, Multicenter, Dose Escalation and Cohort Expansion Study of the Safety and Efficacy of Anti-CD70 Allogeneic CRISPR-Cas9-Engineered T Cells (CTX131) in Adult Subjects With Relapsed or Refractory Solid Tumors

          Conditions
          • Malignant Pleural Mesothelioma
          Interventions
          • Biological: CTX131
          Facility
          • Research Site 3, Duarte, California
          • Research Site 7, Chicago, Illinois
          • Research Site 6, Boston, Massachusetts
          • Research Site 2, Saint Louis, Missouri
          • Research Site 4, Durham, North Carolina
          • Research Site 1, Nashville, Tennessee
          • Research Site 5, Houston, Texas
          Clinical Trial for Advanced Solid Tumor from SpringWorks Therapeutics, Inc.
          Location: Scottsdale, Arizona (multiple locations)
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          Clinical Trial for Advanced Solid Tumor from SpringWorks Therapeutics, Inc.

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          Trial Name
          A Phase 1a/1b Dose Escalation, Dose Expansion Study of SW-682 in Participants With Advanced Solid Tumors Enriched for Those With Hippo Pathway Mutations

          Conditions
          • Mesothelioma, Malignant
          Interventions
          • Drug: SW-682
          Facility
          • SpringWorks Clinical Trial Site, Scottsdale, Arizona
          • SpringWorks Clinical Trial Site, La Jolla, California
          • USC/Norris Comprehensive Cancer Center, Los Angeles, California
          • SpringWorks Clinical Trial Site, Los Angeles, California
          • University Hospitals Cleveland Medical Center, Cleveland, Ohio
          • Knight Cancer Institute Clinical Trials, Portland, Oregon
          • Mary Crowley Cancer Research, Dallas, Texas
          • The University of Texas MD Anderson Cancer Center, Houston, Texas
          Clinical Trial for Solid Tumor, Adult from A2 Biotherapeutics Inc.
          Location: La Jolla, California (multiple locations)
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          Clinical Trial for Solid Tumor, Adult from A2 Biotherapeutics Inc.

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          Trial Name
          A Seamless Phase 1/2 Study to Evaluate the Safety and Efficacy of A2B694, an Autologous Logic-gated Tmod™ CAR T, in Heterozygous HLA-A*02 Adults with Recurrent Unresectable, Locally Advanced, or Metastatic Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

          Conditions
          • Non Small Cell Lung Cancer
          • Mesothelioma
          • Mesothelioma, Malignant
          • Lung Cancer
          Interventions
          • Biological: A2B694
          • Diagnostic Test: xT CDx with HLA-LOH Assay
          Facility
          • UCSD Moores Cancer Center, La Jolla, California
          • UCLA Medical Center, Los Angeles, California
          • Stanford University, Stanford, California
          • Mayo Clinic, Jacksonville, Florida
          • Moffitt Cancer Center, Tampa, Florida
          • Massachusetts General Hopsital/Dana Farber Cancer Center, Boston, Massachusetts
          • Mayo Clinic Rochester, Rochester, Minnesota
          • Washington University, St. Louis, Missouri
          • NYU Langone Medical Center, New York, New York
          • Fred Hutchinson Cancer Center, Seattle, Washington
          Clinical Trial for Thymus Tumors from National Institutes of Health Clinical Center (CC)
          Location: Bethesda, Maryland
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          Clinical Trial for Thymus Tumors from National Institutes of Health Clinical Center (CC)

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          Trial Name
          Inpatient Hospice With Procurement of Tissue on Expiration in Thoracic Malignancies, Bladder Cancer, Ovarian Cancer, Epithelial Cancer and Patients Treated With an Adoptive Cellular Therapy

          Conditions
          • Mesothelioma
          • Lung Cancers
          Facility
          • National Institutes of Health Clinical Center, Bethesda, Maryland
          Clinical Trial for Mesothelioma from Memorial Sloan Kettering Cancer Center
          Location: Basking Ridge, New Jersey (multiple locations)
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          Clinical Trial for Mesothelioma from Memorial Sloan Kettering Cancer Center

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          Trial Name
          Phase 2 Study of Sacituzumab Govitecan-hziy in Patients with Previously Treated Mesothelioma

          Conditions
          • Mesothelioma
          • Mesotheliomas Pleural
          • Mesothelioma; Pleura
          Interventions
          • Drug: Sacituzumab govitecan-hziy
          Facility
          • Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey
          • Memorial Sloan Kettering Monmouth, Middletown, New Jersey
          • Memorial Sloan Kettering Bergen, Montvale, New Jersey
          • Memorial Sloan Kettering Cancer Center @ Commack, Commack, New York
          • Memorial Sloan - Kettering Cancer Center, New York, New York
          • Memorial Sloan Kettering Nassau, Uniondale, New York
          • Memorial Sloan Kettering Westchester, West Harrison, New York
          Clinical Trial for Mesothelioma from University of Chicago
          Location: Chicago, Illinois
          Call (866) 608-8933 to get help enrolling in this clinical trial
          Clinical Trial for Mesothelioma from University of Chicago

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          Trial Name
          Phase II Trial of Olaparib in Homologous Recombination Deficient (HRD) Malignant Mesothelioma

          Conditions
          • Mesothelioma
          Interventions
          • Drug: Olaparib
          Facility
          • University of Chicago Medical Center, Chicago, Illinois
          Clinical Trial for Malignant Pleural Mesothelioma from Oncovir, Inc.
          Location: New York, New York
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          Clinical Trial for Malignant Pleural Mesothelioma from Oncovir, Inc.

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          Trial Name
          Direct Injection of Poly-ICLC (Hiltonol®) Vaccine In Malignant Pleural Mesothelioma

          Conditions
          • Malignant Pleural Mesothelioma
          Interventions
          • Biological: Safety
          Facility
          • Icahn School of Medicine Mount Sinai, New York, New York
          Clinical Trial for Mesotheliomas Pleural from Abramson Cancer Center at Penn Medicine
          Location: Philadelphia, Pennsylvania
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          Clinical Trial for Mesotheliomas Pleural from Abramson Cancer Center at Penn Medicine

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          Trial Name
          Pembrolizumab in Combination With Chemotherapy and Image-Guided Surgery for Malignant Pleural Mesothelioma (MPM)

          Conditions
          • Mesotheliomas Pleural
          Interventions
          • Drug: Pembrolizumab
          • Procedure: Indocyanine Green (ICG) Image-Guided Surgery
          • Drug: Cisplatin
          • Drug: Pemetrexed
          Facility
          • Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania
          Clinical Trial for Mesothelioma from Mirati Therapeutics Inc.
          Location: Phoenix, Arizona (multiple locations)
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          Clinical Trial for Mesothelioma from Mirati Therapeutics Inc.

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          Trial Name
          A Phase 1/2 Multiple Expansion Cohort Trial of MRTX1719 in Patients With Advanced Solid Tumors With Homozygous MTAP Deletion

          Conditions
          • Mesothelioma
          • Non Small Cell Lung Cancer
          Interventions
          • Drug: MRTX1719
          Facility
          • Mayo Clinic, Phoenix, Arizona
          • Sarah Cannon Research Institute (SCRI) - HealthONE Location, Denver, Colorado
          • Local Institution - 109, Lone Tree, Colorado
          • Mayo Clinic, Jacksonville, Florida
          • Sarah Cannon Research Institute at Florida Cancer Specialists, Orlando, Florida
          • Local Institution - 124, Chicago, Illinois
          • Dana-Farber Cancer Institute, Brookline, Massachusetts
          • Mayo Clinic, Rochester, Minnesota
          • Local Institution - 127, New Brunswick, New Jersey
          • David H Koch, Memorial Sloan Kettering Cancer Center, New York, New York
          • New york cancer and blood specialists - Oncology, Port Jefferson Station, New York
          • Local Institution - 125, Chapel Hill, North Carolina
          • SCRI, Nashville, Tennessee
          • Local Institution - 120, Dallas, Texas
          • Local Institution - 111, Dallas, Texas
          • MDACC, Houston, Texas
          • Oncology Consultants - Clinical Research, Houston, Texas
          • South Texas Accelerated Research Therapeutics, San Antonio, Texas
          • Local Institution - 110, Tyler, Texas
          • Virginia Cancer Specialists, PC, Fairfax, Virginia
          • Medical College of Wisconsin - Froedtert Hospital, Milwaukee, Wisconsin
          Clinical Trial for Pancreatic Cancer from University of Nebraska
          Location: Greenwood Village, Colorado (multiple locations)
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          Clinical Trial for Pancreatic Cancer from University of Nebraska

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          Trial Name
          Integrated Cancer Repository for Cancer Research

          Conditions
          • Lung Cancer
          • Peritoneal Surface Malignancies
          • Mesothelioma
          Facility
          • Advent Health, Greenwood Village, Colorado
          • Florida Hospital Memorial Medical Center, Daytona Beach, Florida
          • Florida Hospital DeLand, DeLand, Florida
          • Florida Hospital FISH, Orange City, Florida
          • Florida Hospital Flagler, Palm Coast, Florida
          • Tallahassee Memorial Hospital, Tallahassee, Florida
          • Rush-Copley Cancer Care Center, Aurora, Illinois
          • Rush-Copley Healthcare Center, Yorkville, Illinois
          • Parkview Research Center, Fort Wayne, Indiana
          • Community Health Network, Indianapolis, Indiana
          • Community Cancer Center South, Indianapolis, Indiana
          • Methodist Jennie Edmundson Hospital, Council Bluffs, Iowa
          • Covenant Medical Center, Inc, Waterloo, Iowa
          • Saint Luke's Cancer Instititue - South, Overland Park, Kansas
          • Northwest Hospital, Randallstown, Maryland
          • William E Kahlert Regional Cancer Center, Westminster, Maryland
          • Holyoke Medical Center, Holyoke, Massachusetts
          • University of Michigan Health System, Ann Arbor, Michigan
          • Riverwood Healthcare Center, Aitkin, Minnesota
          • Essentia Health-St. Joseph's Medical Center, Brainerd, Minnesota
          • Essentia Health - Duluth Clinic, Duluth, Minnesota
          • St. Luke's Hospital of Duluth, Duluth, Minnesota
          • Lake Region Healthcare, Fergus Falls, Minnesota
          • Saint Luke's Cancer Institute, East, Kansas City, Missouri
          • Saint Luke's Cancer Institute, Kansas City, Missouri
          • Saint Luke's Cancer Institute, Kansas City North, Kansas City, Missouri
          • Saint Luke's Cancer Institute, Liberty, Liberty, Missouri
          • Heartland Regional Medical Center dba Mosaic Life Care, Saint Joseph, Missouri
          • Bozeman Health Deaconess Hospital, Bozeman, Montana
          • Logan Health, Kalispell, Montana
          • Mary Lanning Healthcare, Morrison Cancer Center, Hastings, Nebraska
          • Faith Regional Health Services, Carson Cancer Center, Norfolk, Nebraska
          • Great Plains Regional Medical Center, North Platte, Nebraska
          • Methodist Estabrook Cancer Center, Omaha, Nebraska
          • Nebraska Methodist Health System, Omaha, Nebraska
          • University of Nebraska Medical Center, Omaha, Nebraska
          • Regional West Health Services, Scottsbluff, Nebraska
          • C.R. Wood Cancer Center, Glens Falls Hospital, Glens Falls, New York
          • Faxton St. Luke's Healthcare, Mohawk Valley, Utica, New York
          • Cape Fear Valley Health System, Fayetteville, North Carolina
          • Essentia Health, Fargo, North Dakota
          • Trinity Hospital Cancer Care Center, Minot, North Dakota
          • Aultman Alliance Community Hospital, Alliance, Ohio
          • Aultman Hospital, Canton, Ohio
          • University of Pittsburgh, Pittsburgh, Pennsylvania
          • Rutland Regional Medical Center, Rutland, Vermont
          • Bellin Memorial Hospital, Green Bay, Wisconsin
          Clinical Trial for Mesothelioma from Baylor College of Medicine
          Location: Durham, North Carolina (multiple locations)
          Call (866) 608-8933 to get help enrolling in this clinical trial
          Clinical Trial for Mesothelioma from Baylor College of Medicine

          Our Patient Advocates can help you connect with clinical trials

          Call (866) 608-8933 to get started

          Trial Name
          Combination of Induction Durvalumab and Tremelimumab Alone Versus Durvalumab and Tremelimumab With Chemotherapy for Potentially Resectable Pleural Mesothelioma

          Conditions
          • Mesothelioma
          Interventions
          • Drug: Durvalumab / tremelimumab
          Facility
          • Duke Cancer Institute, Durham, North Carolina
          • Baylor St Lukes, Houston, Texas
          Clinical Trial for Solid Tumor, Adult from KaliVir Immunotherapeutics
          Location: Los Angeles, California (multiple locations)
          Call (866) 608-8933 to get help enrolling in this clinical trial
          Clinical Trial for Solid Tumor, Adult from KaliVir Immunotherapeutics

          Our Patient Advocates can help you connect with clinical trials

          Call (866) 608-8933 to get started

          Trial Name
          A Phase 1/1b Study of VET3-TGI Administered Alone and in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

          Conditions
          • Mesothelioma
          • Non-small Cell Lung Cancer
          Interventions
          • Drug: VET3-TGI
          Facility
          • USC/Norris Comprehensive Cancer Center, Los Angeles, California
          • University of Miami, Miami, Florida
          • Community Health Network, Indianapolis, Indiana
          • UPMC- Hillman Cancer Center, Pittsburgh, Pennsylvania
          • Mary Crowley Cancer Research, Dallas, Texas
          • University of Texas MD Anderson Cancer Center, Houston, Texas
          Clinical Trial for Solid Tumor, Adult from Vivace Therapeutics, Inc
          Location: Chicago, Illinois (multiple locations)
          Call (866) 608-8933 to get help enrolling in this clinical trial
          Clinical Trial for Solid Tumor, Adult from Vivace Therapeutics, Inc

          Our Patient Advocates can help you connect with clinical trials

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          Trial Name
          Phase 1, Multi-Center, Open-Label Study of VT3989 in Patients With Refractory Locally Advanced or Metastatic Solid Tumors Enriched for Tumors Harboring Mutations of the Neurofibromatosis Type 2 Gene (Mutant NF2 or mNF2)

          Conditions
          • Mesothelioma
          Interventions
          • Drug: VT3989
          Facility
          • University of Chicago Medical Center, Chicago, Illinois
          • Massachusetts General Hospital, Boston, Massachusetts
          • Dana-Farber Cancer Institute, Boston, Massachusetts
          • Memorial Sloan Kettering Cancer Center-, New York, New York
          • MD Anderson Cancer Center, Houston, Texas
          • NEXT Oncology, San Antonio, Texas
          Clinical Trial for Gastric Cancer from University of Pittsburgh
          Location: Pittsburgh, Pennsylvania
          Call (866) 608-8933 to get help enrolling in this clinical trial
          Clinical Trial for Gastric Cancer from University of Pittsburgh

          Our Patient Advocates can help you connect with clinical trials

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          Trial Name
          A Phase 2 Study to Evaluate the Efficacy and Safety of Adoptive Transfer of Autologous Tumor Infiltrating Lymphocytes in Patients With Advanced Solid Cancers

          Conditions
          • Mesothelioma
          Interventions
          • Biological: Tumor Infiltrating Lymphocytes (TIL)
          • Drug: Fludarabine + Cyclophosphamide combination
          Facility
          • UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania
          Clinical Trial for Pancreas Cancer from Dana-Farber Cancer Institute
          Location: Boston, Massachusetts (multiple locations)
          Call (866) 608-8933 to get help enrolling in this clinical trial
          Clinical Trial for Pancreas Cancer from Dana-Farber Cancer Institute

          Our Patient Advocates can help you connect with clinical trials

          Call (866) 608-8933 to get started

          Trial Name
          A Master Protocol of Stereotactic Magnetic Resonance Guided Adaptive Radiation Therapy (SMART)

          Conditions
          • Lung Cancer
          • Mesothelioma
          Interventions
          • Radiation: MR-guided Linac
          Facility
          • Brigham & Women's Hospital, Boston, Massachusetts
          • Dana Farber Cancer Institute, Boston, Massachusetts
          Clinical Trial for Nasopharyngeal Carcinoma from Ascentage Pharma Group Inc.
          Location: Springdale, Arkansas
          Call (866) 608-8933 to get help enrolling in this clinical trial
          Clinical Trial for Nasopharyngeal Carcinoma from Ascentage Pharma Group Inc.

          Our Patient Advocates can help you connect with clinical trials

          Call (866) 608-8933 to get started

          Trial Name
          A Phase I Study of Safety, Pharmacokinetic and Efficacy of Orally Administered APG-5918 in Patients With Advanced Solid Tumors or Hematologic Malignancies

          Conditions
          • Mesothelioma
          Interventions
          • Drug: APG-5918
          Facility
          • Highlands Oncology, Springdale, Arkansas
          Clinical Trial for Head and Neck Carcinoma from VM Oncology, LLC
          Location: Santa Rosa, California (multiple locations)
          Call (866) 608-8933 to get help enrolling in this clinical trial
          Clinical Trial for Head and Neck Carcinoma from VM Oncology, LLC

          Our Patient Advocates can help you connect with clinical trials

          Call (866) 608-8933 to get started

          Trial Name
          An Open-Label, Multiple-Dose, Dose-Escalation Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of VMD-928 in Subjects With Solid Tumors or Lymphoma

          Conditions
          • Lung Cancer
          • Mesothelioma
          Interventions
          • Drug: VMD-928 300 mg Tablet (ongoing); 100 mg Capsule (complete)
          Facility
          • Providence Medical Foundation, Santa Rosa, California
          • Hartford Hospital, Hartford, Connecticut
          • Memorial Cancer Institute at Memorial Healthcare Systems, Pembroke Pines, Florida
          • Englewood Hospital and Medical Center, Englewood, New Jersey
          • Summit Medical Group, Florham Park, New Jersey
          • Atlantic Health System, Morristown Medical Center, Morristown, New Jersey
          • Presbyterian Kaseman Hospital, Albuquerque, New Mexico
          • Cayuga Medical Center, Ithaca, New York
          • Weill Cornell Medicine, Cornell University, New York, New York
          • Taylor Cancer Research Center, Maumee, Ohio
          • Cancer Care Associates of York, York, Pennsylvania
          • The University of Texas MD Anderson Cancer Center, Houston, Texas
          • Utah Cancer Specialists, Salt Lake City, Utah
          Clinical Trial for Unresectable Pleural Mesothelioma from AstraZeneca
          Location: Phoenix, Arizona (multiple locations)
          Call (866) 608-8933 to get help enrolling in this clinical trial
          Clinical Trial for Unresectable Pleural Mesothelioma from AstraZeneca

          Our Patient Advocates can help you connect with clinical trials

          Call (866) 608-8933 to get started

          Trial Name
          A Phase III, Randomized, Open-Label, Multicenter, Global Study of Volrustomig (MEDI5752) in Combination With Carboplatin Plus Pemetrexed Versus Platinum Plus Pemetrexed or Nivolumab Plus Ipilimumab in Participants With Unresectable Pleural Mesothelioma (eVOLVE-Meso)

          Conditions
            Interventions
            • Drug: Volrustomig
            • Drug: Pemetrexed
            • Drug: Carboplatin
            Facility
            • Research Site, Phoenix, Arizona
            • Research Site, Duarte, California
            • Research Site, Santa Rosa, California
            • Research Site, Aurora, Colorado
            • Research Site, Jacksonville, Florida
            • Research Site, Atlanta, Georgia
            • Research Site, Chicago, Illinois
            • Research Site, Baltimore, Maryland
            • Research Site, Rochester, Minnesota
            • Research Site, Saint Louis, Missouri
            • Research Site, East Brunswick, New Jersey
            • Research Site, Commack, New York
            • Research Site, Valhalla, New York
            • Research Site, Cleveland, Ohio
            • Research Site, Cleveland, Ohio
            • Research Site, Cleveland, Ohio
            • Research Site, Columbus, Ohio
            • Research Site, Independence, Ohio
            • Research Site, Portland, Oregon
            • Research Site, Portland, Oregon
            • Research Site, Portland, Oregon
            • Research Site, Philadelphia, Pennsylvania
            • Research Site, Houston, Texas
            • Research Site, Fairfax, Virginia
            Clinical Trial for Gastric Cancer from HiFiBiO Therapeutics
            Location: Scottsdale, Arizona (multiple locations)
            Call (866) 608-8933 to get help enrolling in this clinical trial
            Clinical Trial for Gastric Cancer from HiFiBiO Therapeutics

            Our Patient Advocates can help you connect with clinical trials

            Call (866) 608-8933 to get started

            Trial Name
            A Phase 1a/1b, Open-Label, Multi-Center, Dose Escalation and Expansion Study of HFB200301 (TNFR2 Agonist Antibody) as a Single Agent and in Combination With Tislelizumab (Anti-PD-1 Antibody) in Adult Patients With Advanced Solid Tumors

            Conditions
            • Mesothelioma
            • Non Small Cell Lung Cancer
            Interventions
            • Drug: HFB200301
            Facility
            • Mayo Clinic, Scottsdale, Arizona
            • USC/Norris Comprehensive Cancer Center, Los Angeles, California
            • Mayo Clinic, Jacksonville, Florida
            • Mayo Clinic, Rochester, Minnesota
            • Washington University School of Medicine, Saint Louis, Missouri
            • The University of Texas, MD Anderson Cancer Center, Houston, Texas
            • NEXT Virginia Cancer Specialists, Fairfax, Virginia
            Clinical Trial for Carcinoma, Non-Small-Cell Lung from Seagen Inc.
            Location: Nashville, Tennessee (multiple locations)
            Call (866) 608-8933 to get help enrolling in this clinical trial
            Clinical Trial for Carcinoma, Non-Small-Cell Lung from Seagen Inc.

            Our Patient Advocates can help you connect with clinical trials

            Call (866) 608-8933 to get started

            Trial Name
            A Phase 1 Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of PF-08052666/SGN-MesoC2 in Participants With Advanced Solid Tumors

            Conditions
            • Mesothelioma
            Interventions
            • Drug: PF-08052666
            Facility
            • SCRI Oncology Partners, Nashville, Tennessee
            • South Texas Accelerated Research Therapeutics, San Antonio, Texas
            • START Mountain Region, West Valley City, Utah
            Clinical Trial for Pancreatic Cancer from Takeda
            Location: Birmingham, Alabama (multiple locations)
            Call (866) 608-8933 to get help enrolling in this clinical trial
            Clinical Trial for Pancreatic Cancer from Takeda

            Our Patient Advocates can help you connect with clinical trials

            Call (866) 608-8933 to get started

            Trial Name
            An Open-label, Dose Escalation and Expansion, Phase 1/2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of TAK-500, a Novel Stimulator of Interferon Genes Agonist, as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Select Locally Advanced or Metastatic Solid Tumors

            Conditions
            • Mesothelioma
            • Non-small Cell Lung Cancer (NSCLC), Non-squamous
            Interventions
            • Drug: TAK-500
            Facility
            • Univeristy of Alabama at Birmingham, Birmingham, Alabama
            • City of Hope Comprehensive Cancer Center, Duarte, California
            • University of California San Diego, La Jolla, California
            • University of Colorado - Anschutz Medical Campus - PPDS, Aurora, Colorado
            • Sarah Cannon Research Institute, Denver, Colorado
            • Sylvester Comprehensive Cancer Center, Miami, Florida
            • Northwestern, Chicago, Illinois
            • Dana Farber Cancer Institute, Boston, Massachusetts
            • New York University, New York, New York
            • Fox Chase Cancer Center, Philadelphia, Pennsylvania
            • Sarah Cannon Cancer Institute, Nashville, Tennessee
            • START South Texas Accelerated Research Therapeutics, San Antonio, Texas
            Clinical Trial for Advanced Renal Cell Carcinoma from M.D. Anderson Cancer Center
            Location: Houston, Texas
            Call (866) 608-8933 to get help enrolling in this clinical trial
            Clinical Trial for Advanced Renal Cell Carcinoma from M.D. Anderson Cancer Center

            Our Patient Advocates can help you connect with clinical trials

            Call (866) 608-8933 to get started

            Trial Name
            Phase I/II Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma

            Conditions
              Interventions
              • Drug: CAR.70/IL15-transduced CB-derived NK cells
              • Drug: Fludarabine phosphate
              • Drug: Cyclophosphamide
              Facility
              • M D Anderson Cancer Center, Houston, Texas
              of Don't see what you're looking for? Contact us so one of our Patient Advocates can help you find the right clinical trial.

              How Can Mesothelioma Clinical Trials Help Me?

              Clinical trials for mesothelioma can provide more treatment options and give you hope if standard therapies aren’t working.

              Mesothelioma clinical trials can also:

              • Allow you to receive care from top cancer specialists
              • Potentially extend your life expectancy by months or even years
              • Provide a chance for you to contribute to mesothelioma research

              Some treatments being tested in clinical studies may also help improve your quality of life by reducing pain, managing symptoms, or easing side effects from conventional therapies.

              Emerging Treatments Being Tested in Mesothelioma Clinical Trials

              Researchers continue to explore emerging treatments to help mesothelioma patients live longer and manage their symptoms more effectively. If a treatment shows promise in a clinical trial, it could become a standard therapy.

              Treatments being tested in clinical trials include:

              • Gene therapy: New genes are added to cancer cells to make them easier to attack.
              • Mesothelioma vaccines: Certain vaccines can help the immune system destroy mesothelioma cells.
              • Photodynamic therapy: A light-activated drug is injected into the body to kill cancer cells.
              • Targeted therapies: Specialized treatments attack mesothelioma cells without damaging the body’s healthy cells.

              “Ongoing research trials are looking at different immunotherapies and targeted therapies, specifically for patients who harbor unusual mutations in the DNA of their particular tumor type.”

              Dr. Edward Levine, mesothelioma specialist at Atrium Health Wake Forest Baptist

              Use our Free Doctor Match service to connect with a specialist who can help you decide if a clinical trial is right for you.

              Get Matched With a Mesothelioma Doctor
              • Find top specialists near you
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              • Get medical guidance

              Get Matched Now

              Get Matched With a Mesothelioma Doctor

              Are Mesothelioma Clinical Trials Safe?

              Yes, clinical trials for mesothelioma are highly regulated by the FDA to protect patients’ health and safety.

              Key safety measures include:

              • Only enrolling patients after a treatment is proven safe in laboratory tests
              • Providing a consent form to make sure patients understand any risks and potential side effects
              • Requiring several phases of testing before opening trials to large groups of patients

              Top mesothelioma cancer centers also have safety protocols for clinical trials to reduce the risk of complications.

              If you join a mesothelioma clinical trial, you’ll receive information about the potential benefits and drawbacks. You’ll be given time to review these details before deciding whether to move forward.

              Clinical Trials for Mesothelioma Video Thumbnail

              Amy Fair, a nurse with over 20 years of mesothelioma experience, explains what clinical trials are, the types, and how to find them. View Transcript.

              Duration: 1 min 31 sec

              Besides the standard treatment right now of radiation, surgery, and chemotherapy there are ongoing clinical trials at some facilities that some patients may fit.

              Clinical trials are the development of new and novel therapies.

              You have to be a candidate and meet certain criterial for clinical trials. Some trials evolve around a certain type of mesothelioma. Some evolve around a certain age group.

              There are exciting clinical trials out there now that involved immunotherapy, where they are strengthening and enhancing someone’s immune system to fight the disease. There are target and gene therapies currently in clinical trials that target someone’s DNA make up and molecular studies. These are still currently in several phases of clinical trials.

              If you are interested in a clinical trial or your oncologist thinks you’re a candidate for a clinical trial the best way to learn is to start with your oncologist. They should be very knowledgeable about the clinical trials in your area. The National Institute of Health, on their website, has a tremendous amount of knowledge about clinical trials, the different phases that they are in and where these facilities are at that are involved in these clinical trials.

              Mesothelioma Clinical Trial Phases

              Clinical trials for mesothelioma typically have multiple phases, each with a specific purpose. As the phases progress and safety is confirmed, the number of patients enrolled may increase.

              • Phase I trials are designed to find a safe dose of the new treatment, determine how it should be given, and learn how it affects the body. If a safe dose is found, the new treatment moves to phase II testing.
              • Phase II trials study how the treatment affects the body and how well it works for mesothelioma. If a new treatment is deemed safe and may help patients, it proceeds to phase III.
              • Phase III trials compare the new mesothelioma treatment with the current standard treatment to see which one is better. The results are submitted to the FDA for review.
              • Phase IV trials evaluate the long-term benefits and risks of the new treatment once it obtains FDA approval.

              Not all mesothelioma clinical trials go through all four phases. Some may combine phases (e.g., Phase I/II or Phase II/III) depending on the study’s goals.

              5 Questions to Ask Your Doctor About Mesothelioma Clinical Trials

              Talking to your doctor can help you make an informed decision about whether or not to join a mesothelioma clinical trial. It’s important to go into this conversation with specific questions in mind.

              Here are 5 questions you can ask:

              1. Has this treatment been used on other patients?
              2. What are the benefits and risks of participating in this trial?
              3. How might this study impact my daily life and current treatment plan?
              4. Where will I need to go to participate in this trial?
              5. What follow-up care does this clinical trial include?

              Use these questions to help ensure you leave your appointment with a clear understanding of how the trial may help you and whether it makes sense to move forward.

              Download our Free Checklist for 14 more questions you should ask your doctor about your mesothelioma treatment plan.

              14 Questions to Ask Your Doctor packet
              Free Download: 14 Questions to Ask Your Doctor
              • Preparing for treatment
              • Finding clinical trials
              • Getting a second opinion

              Get Your Free Download

              What to Expect After Joining a Mesothelioma Clinical Trial

              Clinical trials can give you more options for treatment, but it helps to know what the process involves.

              • Randomized treatment: In some trials, you might be randomly assigned a standard treatment instead of the new treatment. You and your doctor won’t be told which one you’re getting to ensure the accuracy of the trial results.
              • Regular check-ups: You’ll have routine visits where your doctor will monitor your progress and ask if you have any side effects.
              • Scans & blood tests: Your doctor might order new imaging scans or blood tests to see how well the treatment is working.
              • Flexibility to withdraw: You can stop participating at any time, especially if you have serious side effects or if your cancer doesn’t respond.
              • Follow-up care: After the trial ends, your doctor will evaluate you to see how your cancer responded to treatment.

              Participating in a clinical trial is a personal decision, and it’s important to choose what feels right for you and your health.

              Get Help Finding the Right Mesothelioma Clinical Trial

              Mesothelioma clinical trials provide hope by giving you access to innovative treatments that may grant you more time with loved ones.

              However, finding and enrolling in clinical trials can be a confusing process, with multiple options, phases, and medical terms to decipher. That’s where we step in to simplify the process.

              Mesothelioma Hope is here to:

              • Connect you with top specialists for treatment
              • Recommend clinical trials based on your diagnosis
              • Guide you on how to manage any side effects

              Contact us today at (866) 608-8933 or use our Free Doctor Match service to get started.

              Clinical Trials for Mesothelioma FAQs

              Are there any new clinical trials for mesothelioma?

              Yes, there are over 60 active mesothelioma clinical trials in the U.S. as of January 2025.

              These include studies exploring combinations of chemotherapy and immunotherapy drugs like Keytruda® and Tecentriq®, as well as other emerging treatments such as gene therapy and targeted therapies.

              What is the new drug trial for mesothelioma?

              The ATOMIC-Meso clinical trial tests the new drug pegargiminase (ADI-PEG20) combined with traditional chemotherapy. ADI-PEG20 works by starving mesothelioma cells of the nutrients they need to grow.

              The results so far are impressive: Combining ADI-PEG20 with chemotherapy quadrupled the 3-year survival rate compared to chemotherapy alone​.

              Are there any active peritoneal mesothelioma clinical trials in 2025?

              Yes. As of January 2025, there are 9 peritoneal mesothelioma clinical trials that are still actively recruiting patients.

              One example is the Phase II ICARuS trial, which is studying whether patients with peritoneal mesothelioma can benefit from additional rounds of chemotherapy with pemetrexed and cisplatin after cytoreductive surgery with heated chemotherapy.

              What are some recently completed mesothelioma clinical trials?

              Mesothelioma clinical trials that were completed in the last year include:

              • A phase I/II trial tested Gavo-cel, a type of immunotherapy designed to target mesothelin in mesothelioma cells. Several patients in the study had their cancer stabilize.
              • A phase II clinical trial explored a targeted galinpepimut-S (GPS) vaccine. Data showed this combination helped mesothelioma patients live three times longer.
              • The phase III ATOMIC-Meso trial combined a new drug, pegargiminase (ADI-PEG20), with traditional chemotherapy. This approach quadrupled survival at 36 months compared to chemotherapy alone.

              What is the wonder drug for mesothelioma?

              There is no single “wonder drug” for mesothelioma, but Keytruda (pembrolizumab) and Opdivo (nivolumab), which are both immunotherapy drugs, have shown significant promise in helping mesothelioma patients live longer.

              Does it cost money to join clinical trials for mesothelioma?

              No, it typically doesn’t cost anything to join clinical trials for mesothelioma. Clinical trials are usually paid for by research institutions, pharmaceutical companies, or government agencies.

              However, depending on where the trial is located, you may need to pay for travel, transportation, or lodging.

              Dr. Mark LevinReviewed by:Mark Levin, MD

              Certified Oncologist and Hematologist

              • Fact-Checked
              • Editor

              Mark Levin, MD, has over 30 years of experience in academic and community hematology and oncology. In addition to serving as Chief or Director at four different teaching institutions throughout his life, he is still a practicing clinician, has taught and designed formal education programs, and has authored numerous publications in various fields related to hematology and oncology.

              Dr. Mark Levin is an independently paid medical reviewer.

              • Board Certified Oncologist
              • 30+ Years Experience
              • Published Medical Author
              Jenna TozziWritten by:

              Chief Patient Care Advisor

              Jenna Tozzi, RN, is the Chief Patient Care Advisor for Mesothelioma Hope. With more than 15 years of experience as an adult and pediatric oncology nurse navigator, Jenna provides exceptional guidance and support to cancer patients and their loved ones. Jenna has been featured in Oncology Nursing News and is a member of the Academy of Oncology Nurse & Patient Navigators & the American Nurses Association.

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              References
              1. American Cancer Society. “What’s New in Malignant Mesothelioma Research?” Retrieved December 19, 2024, from https://www.cancer.org/cancer/malignant-mesothelioma/about/new-research.html
              2. Canadian Cancer Society, “Clinical Trials.” Retrieved December 19, 2024, from http://www.cancer.ca/en/cancer-information/diagnosis-and-treatment/clinical-trials/?region=on
              3. ClinicalTrials.gov, “Olaparib in People With Malignant Mesothelioma” Retrieved December 19, 2024, from https://clinicaltrials.gov/ct2/show/NCT03531840?cond=Mesothelioma&rank=8
              4. ClinicalTrials.gov, “Pevonedistat Alone and in Combination with Chemotherapy in Patients with Mesothelioma.” Retrieved December 19, 2024, from https://clinicaltrials.gov/ct2/show/NCT03319537?cond=mesothelioma&draw=2&rank=11
              5. Mielgo-Rubio X, Cardeña Gutiérrez A, Sotelo Peña V, Sánchez Becerra MV, González López AM, Rosero A, Trujillo-Reyes JC, Couñago F. “Tsunami of immunotherapy reaches mesothelioma.” World Journal of Clinical Oncology. 2022 Apr 24;13(4):267-275. doi: 10.5306/wjco.v13.i4.267. Retrieved December 19, 2024, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9052072/
              6. Paolo Andrea Zucali, Fabio De Vincenzo, Matteo Perrino, Nunzio Digiacomo, Nadia Cordua, Federica D’Antonio, Federica Borea, Roberta Fazio, Angelo Pirozzi & Armando Santoro (2022). “Advances in drug treatments for mesothelioma, Expert Opinion on Pharmacotherapy.” 23:8, 929-946, DOI: 10.1080/14656566.2022.2072211. Retrieved December 19, 2024, from https://www.tandfonline.com/doi/abs/10.1080/14656566.2022.2072211
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