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Dr. Edward A. Levine

Surgical Oncologist

Dr. Edward A. Levine is a surgical oncologist who has spent more than 25 years treating patients with peritoneal mesothelioma. He currently leads the hyperthermic intraperitoneal chemotherapy (HIPEC) team at Wake Forest Baptist Medical Center in North Carolina, where he has improved the length and quality of life for hundreds of peritoneal mesothelioma patients. Learn more about Dr. Levine and get our help connecting with him today.

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About Dr. Edward Levine

Dr. Levine has substantial involvement in research trials investigating his patients’ quality of life upon completing cytoreductive surgery with HIPEC. He has also studied survival outcomes, tumor genomics, and the types of chemotherapy drugs administered throughout the HIPEC procedure.

Dr. Levine is a board-certified physician nationally recognized for:

“The HIPEC procedure represents a significant advance in the approach of patients who have had tumors which have spread inside the peritoneal cavity and other places. This gives us real options with the hope of long-term, disease-free survival with good quality of life.”

- Dr. Edward Levine

Dr. Levine’s Reviews by Patients

Dr. Levine’s patients unequivocally celebrate Dr. Levine’s outstanding expertise, compassionate care, and exceptional ability to instill trust.

Many commend him for his aptitude to convey complex medical concepts in easily digestible terms, contributing to his patient’s overall comfort and confidence.

His calming demeanor, genuine concern, and interest in their well-being strengthen this trust bond. Described as one of the best doctors by several patients, he is also lauded for his anticipatory care – often addressing concerns before they are voiced. Compliments aren’t just limited to his medical proficiency; many deeply appreciate his personal touch, whether it’s a moment he takes to view family photos or the wit he displays that act as a balm in anxious times.

“Dr. Levine had answers to all my questions before I even asked them. He calmed my nerves and made me feel good about my prognosis. I had heard he was the best and after my visit I trust him with my care.”
– A Patient of Dr. Levine, Sep. 2023

Notably, Dr. Levine’s excellence isn’t limited to patient interaction. His surgical skills are acclaimed, with numerous testimonials attesting to his technical expertise and holistic approach to patient care. While his busy schedule is occasionally highlighted, it’s often understood within the context of his dedication to medical education and his commitment to providing detailed insights to his patients.

“Beyond his medical expertise — which saved my life — Dr. Levine brings even greater humanity, compassion, kindness, humor, and hope — which is what life is all about.”
– A Patient of Dr. Levine, Apr. 2023

His team and staff, mirroring his ethos, are often mentioned for their professionalism and kindness. A few critiques do emerge, notably about the surrounding care environment and potential oversights, but they appear as exceptions in the sea of praise. His international recognition as a top-tier cancer physician only adds to the sentiment that many feel privileged and grateful to have Dr. Levine at the helm of their medical journey.

Above all, the recurring theme is clear: Dr. Levine is not just a doctor but a beacon of hope, comfort, and confidence for those navigating the challenging terrain of medical concerns.

Dr. Levine’s Career Highlights

Dr. Levine has had an extensive career dedicated to advancing chemotherapy technologies for mesothelioma patients.

His career highlights include:

  • Helping lead one of the world’s largest quality-of-life studies for HIPEC patients
  • Leading the heated chemotherapy program at Atrium Health Wake Forest Baptist
  • Researching new HIPEC chemotherapy agents to help expand treatment options

Dr. Levine’s Background

Dr. Levine began his post-secondary education at Northern Illinois University, graduating with a bachelor of science degree. He holds a medical degree from Rosalind Franklin University of Medicine and Science.

Two years after completing a general surgical residency at Michael Reese Hospital in Chicago, he completed another residency in oncology at the University of Illinois Hospital.

Dr. Levine worked at Louisiana State University before joining the Comprehensive Cancer Center at Atrium Health Wake Forest Baptist in North Carolina.

During his time at Atrium Health, Dr. Levine has made significant contributions toward the understanding and treatment of peritoneal mesothelioma. His research has covered many topics and resulted in more than 150 published works, many focusing on mesothelioma and HIPEC.

Medical Specializations

Dr. Levine is a surgical oncologist specializing in peritoneal diseases. Alongside the HIPEC team at Atrium Health Wake Forest Baptist, he has performed the procedure on over 1,000 patients. HIPEC is widely considered the most successful method of treating peritoneal mesothelioma.

“Wake Forest Baptist Medical Center enjoys one of the largest experiences in the world with cytoreductive surgery and Hyperthermic Intraperitoneal Chemotherapy.”

- Dr. Edward Levine

Dr. Levine is widely recognized for his work specializing in treating mesothelioma cancer but also specializes in rare appendix and colon cancers.

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Dr. Levine’s Career Accomplishments

Dr. Levine stands out in the medical community for his extensive knowledge of mesothelioma. He has also completed numerous research trials on mesothelioma and other peritoneal conditions, some of which have focused on patient quality of life and increasing survival outcomes.

“To patients, I would say that even though your type of tumor is rare, with only about 3,000 new cases per year, don’t feel alone. There is active research taking place for this type of cancer.”

- Dr. Edward Levine

Awards & Honors

Dr. Levine’s awards and honors include:

  • American Chemical Society Fellow
  • Best Doctors In America
  • CMS Meaningful Use Stage 1 Certification
  • EpicCare Inpatient – Core EMR
  • Top Doctor for Cancer

Dr. Levine’s Current Work

Dr. Levine currently serves as chief of surgical oncology at Wake Forest University. Since 1998, he has also educated the next generation of surgical oncologists at Wake Forest University as a professor of surgery.

His work has received numerous grants for his research into the genomics of tumors. Organizations like the National Surgical Breast and Bowel Project and the American College of Surgeons Oncology Group support Dr. Levine’s work.

Dr. Levine is also a member of many organizations, including:

  • Alpha Omega Alpha
  • American Association of Clinical Oncology
  • American College of Surgeons
  • American Hepato-Pancreato-Biliary Association
  • Association of Academic Surgery
  • Connective Tissue Oncology Society
  • North Carolina Medical Society
  • Society for Surgery of the Alimentary Tract
  • Society of Surgical Oncology
  • Southern Surgical Association

Notable Work by Dr. Levine

Dr. Levine has researched survival rates for patients with diffuse malignant peritoneal mesothelioma.

In a collaborative effort, he published an article discussing his development of a two-tier system using the number of epithelioid cells in peritoneal mesothelioma cases that analyzes patients’ survival rates. The study categorized the tumors into low-grade or high-grade based on the microbiology of the cells and then plotted their survival rate.

The study ultimately concluded that patients with low-grade diffuse peritoneal mesothelioma lived for several years longer after treatment than those with high-grade diffuse mesothelioma.

Dr. Levine’s work in this area is important because peritoneal mesothelioma previously did not have an effective staging system compared to pleural mesothelioma.

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Dr. Levine’s Healing Philosophy

Dr. Levine encourages patients to get well-prepared before and after undergoing mesothelioma treatments.

“Come to this treatment in the best possible shape. By that, I mean not just physiologically and nutritionally but also your mental and spiritual states — all of these are important. The better the shape you are in, the better the outcome.”

- Dr. Edward Levine

He also stresses the importance of relationships with your mesothelioma doctors and medical team.

Get to know your surgeon, talk about what to expect, and get to know the hospital you will be spending time in. Both the patients and caregivers need to know their surroundings and their surgeon to keep stress in check and to take care of themselves as well as possible while going through surgery.”

- Dr. Edward Levine

We can help you connect with top mesothelioma doctors now. Call (866) 608-8933 to start the process.

Mesothelioma Hope has no affiliation with and is not endorsed or sponsored by Dr. Edward A. Levine. Any contact information listed is for informational purposes only. You have the right to contact Dr. Edward A. Levine directly.

Jenna TozziWritten by:

Director of Patient Advocacy

Jenna Tozzi, RN, is the Director of Patient Advocacy at Mesothelioma Hope. With more than 15 years of experience as an adult and pediatric oncology nurse navigator, Jenna provides exceptional guidance and support to mesothelioma patients and their loved ones. Jenna has been featured in Oncology Nursing News and is a member of the Academy of Oncology Nurse & Patient Navigators & the American Nurses Association.

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  1. Atrium Health Wake Forest Baptist. “Edward A. Levine, M.D.” Retrieved from Accessed on May 29, 2024.
  2. Linkedin. “Edward Levine.” Retrieved from: Accessed on May 29, 2024.
  3. Valente, K., Blackham, A. U., Levine, E., Russell, G., Votanopoulos, K. I., Stewart, J. H., Shen, P., Geisinger, K. R., & Sirintrapun, S. J. (2016). A Histomorphologic Grading System That Predicts Overall Survival in Diffuse Malignant Peritoneal Mesothelioma With Epithelioid Subtype. The American journal of surgical pathology, 40(9), 1243–1248. Retrieved from: Accessed on May 29, 2024.
  4. YouTube. “A National Leader in Hyperthermic Intraperitoneal Chemotherapy.” Retrieved from: Accessed on May 29, 2024.
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