Mesothelioma Latency Period

The mesothelioma latency period is the amount of time between asbestos exposure and a mesothelioma diagnosis. The average latency period for mesothelioma is 10-50 years but may be longer or shorter based on your gender, your age when you were first exposed to asbestos, and other factors. Learn more about the mesothelioma latency period and how we can help you or a loved one get an accurate diagnosis.

Fact-Checked and Updated by: Jenna Tozzi, RN

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What Is the Latency Period for Mesothelioma?

The latency period for mesothelioma is the time between the initial asbestos exposure and a diagnosis.

Once you breathe in or swallow asbestos fibers, there’s no way for your body to get rid of them. Asbestos can irritate the lining of the lungs and other tissues for 10-50 years before triggering symptoms of mesothelioma.

This longer latency period is the main reason why most people diagnosed with mesothelioma are over the age of 65.

“Because of the latency period between asbestos exposure and developing mesothelioma, a lot of patients are elderly.”

Dr. Joseph Friedberg, mesothelioma specialist at Fox Chase Cancer Center

Why Does Mesothelioma Have Such a Long Latency Period?

There are several reasons why mesothelioma cancer takes a long time to develop:

  • Body’s Repair Efforts: The body tries to repair the internal damage caused by asbestos. At first, these repairs are effective, but over time, the damage accumulates faster than the body can fix it.
  • Chronic Inflammation: Asbestos fibers cause persistent, low-level inflammation rather than sudden, severe damage. This ongoing irritation gradually affects the body’s internal tissues.
  • Symptoms: The early symptoms of mesothelioma, like a slight cough or shortness of breath, are often mild and easy to overlook. These symptoms can be mistaken for less serious issues, delaying a diagnosis.
  • Slow Cellular Changes: The cell damage and genetic mutations caused by asbestos exposure don’t occur overnight. It takes several years for asbestos fibers to disrupt normal cell functions.

Understanding these factors helps explain why asbestos-related diseases take so long to develop and highlights the importance of regular health check-ups, especially for those who have been exposed to asbestos.

Get our Free Mesothelioma Guide to learn more about this cancer and what to do if you think you might have been exposed to asbestos.

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What Factors Affect the Mesothelioma Latency Period?

The latency period for mesothelioma is influenced by many factors. This includes the extent of asbestos exposure, where it happened, and individual characteristics that may make the latency period longer or shorter.

Concentration of Asbestos

Higher levels of asbestos exposure may result in a shorter latency period for mesothelioma, though everyone’s experience is different.

Anyone who’s worked in environments with high asbestos levels, such as certain industrial settings, face a greater risk. This is especially true for workers in enclosed areas with poor ventilation.

Frequency of Asbestos Exposure

The extent and duration of exposure to asbestos can directly impact the mesothelioma latency period.

For example, those involved in the production of asbestos-containing products or working in asbestos factories tend to have shorter latency periods.

Those who lived near asbestos mines faced continued environmental asbestos exposure but at a lower level.

Type of Asbestos Exposure

Being around areas with asbestos doesn’t necessarily put you at risk of developing an asbestos-related disease. It’s when asbestos products are disturbed and release fibers into the air that it becomes dangerous.

The higher the intensity of asbestos exposure through certain activities, the greater the risk to a person’s health. Higher exposure levels can result in a shorter latency period for asbestos-related diseases.

The main types of asbestos exposure include:

  • Occupational Exposure: Jobs in construction, shipbuilding, and manufacturing where asbestos materials are used or disturbed. Workers may handle, cut, or repair asbestos-containing products, releasing fibers into the air.
  • Military Exposure: Veterans are at high risk of asbestos exposure due to the extensive use of asbestos-containing materials on Navy ships, submarines, and in military buildings.
  • Product Exposure: Using consumer products that contain asbestos, such as talcum powder, can directly expose the body or skin.
  • Environmental Exposure: Living near asbestos mines or processing plants can result in nearby residents breathing in airborne asbestos fibers. Additionally, natural deposits of asbestos in certain areas can pose a risk when disturbed.
  • Secondary Exposure: Family members of workers exposed to asbestos are also at risk of mesothelioma. Asbestos fibers brought home on clothing, shoes, or hair can cause secondary asbestos exposure.

Our team can help you determine if and how you were exposed to asbestos — even if you don’t remember. Contact us today to get answers.

Other Factors in the Mesothelioma Latency Period

While there’s a clear link between the amount of asbestos exposure and how long it takes for mesothelioma to develop, other personal and health factors can also play a role.

Age and Gender

Men make up more than 80% of all mesothelioma cases because they were more likely to work in jobs where asbestos was heavily used. This direct asbestos exposure can lead to a shorter mesothelioma latency period.

Women can also be exposed to asbestos, both at home and at work. Many women experienced secondary exposure when male family members brought asbestos fibers home on their clothing or work tools. However, this lower level of exposure can make it take longer for mesothelioma to develop.

The age when someone is first exposed to asbestos also matters. Older patients tend to develop mesothelioma sooner after exposure, while younger patients often have a longer period before they start having symptoms.

High-Risk Occupations

When asbestos is disturbed and becomes airborne, anyone who breathes it in or swallows it is at risk. However, certain occupations have higher risks from direct exposure, which may lead to a shorter mesothelioma latency period.

Here are some of the most at-risk occupations:

Anyone who worked in high-risk occupations up until the early 1980s should be particularly vigilant about their health given the increased likelihood of asbestos exposure.

Existing Health Issues

Other health problems can affect how quickly malignant mesothelioma develops.

People with weakened immune systems or other medical conditions may see the disease progress faster since their bodies can’t repair asbestos damage as effectively.

How Latency Period Affects a Mesothelioma Diagnosis

The latency period for mesothelioma can make it harder to get an accurate diagnosis. Because symptoms take so long to appear, doctors might not immediately suspect mesothelioma — especially if they’re unaware of the patient’s asbestos exposure history.

As a result, it’s common for mesothelioma to be misdiagnosed as more common illnesses like pneumonia or lung cancer. The extensive latency period for mesothelioma can also cause later-stage diagnoses, which complicates treatment.

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Latency Period of Mesothelioma vs. Other Asbestos Diseases

Other asbestos-related diseases also have long latency periods and can take multiple decades to develop after initial exposure:

  • Asbestosis is a chronic lung condition caused by inhaling asbestos fibers, with symptoms often appearing 10-50 years after initial exposure.
  • Lung cancer can be caused by asbestos, though it’s usually linked to smoking. Lung cancer from asbestos exposure has a latency period of 10-50 years.
  • Pleural plaques are non-cancerous but may present a higher mesothelioma risk. The latency period ranges from 20-30 years.

Because these diseases share similar symptoms, it’s important to be thoroughly examined by a specialist who can confirm your diagnosis.

The Importance of Early Screening for Mesothelioma

Early screening is key to improving your mesothelioma prognosis. The sooner you catch the signs of this disease, the sooner you can begin treatment that can help extend your life expectancy.

While only a biopsy can confirm a mesothelioma diagnosis, you can also undergo imaging scans like X-rays or CT scans and lung function tests to check for early signs of mesothelioma or other asbestos-related diseases.

Your health care provider may also give you a questionnaire to determine the need for further testing based on your symptoms and asbestos exposure history.

We Can Help You Get Tested for Mesothelioma

If you think you may have been exposed to asbestos, don’t wait to get tested for mesothelioma. Early detection and treatment are key to managing this cancer effectively.

The Mesothelioma Hope team has been providing personalized medical guidance, financial assistance, and supportive care to patients and their families for over 20 years.

We can help you or a loved one:

  • Connect with specialists who provide diagnostic tests for mesothelioma
  • Access compensation to cover medical expenses and treatment
  • Receive emotional support to manage life with mesothelioma

Call us now at (866) 608-8933 or request your Free Mesothelioma Guide to get your questions answered and determine your next steps.

Mesothelioma Latency Period FAQs

How long does it take for mesothelioma to develop?

It generally takes 10-50 years for mesothelioma to develop after asbestos exposure. This timeframe is called the latency period.

The latency period for mesothelioma can vary depending on how much asbestos someone was exposed to and for how long. Other factors like genetics and existing health conditions can also play a role.

One of the challenges with mesothelioma is that early symptoms are often vague and can be mistaken for other common illnesses. This makes early detection difficult. Understanding this long latency period can help explain why mesothelioma is often diagnosed at a later stage.

Is mesothelioma fast growing?

Mesothelioma is generally not considered fast-growing. It usually develops slowly over many years.

However, once symptoms appear and the disease is diagnosed, it can spread rapidly through blood, tissue, and lymph nodes to other parts of the body.

What is the latency period of peritoneal mesothelioma?

The latency period for peritoneal mesothelioma is the same as the pleural mesothelioma latency period, which is typically 10-50 years.

This extended latent period means that someone exposed to asbestos might not develop symptoms or be diagnosed with peritoneal or pleural mesothelioma until many decades later.

Can mesothelioma lie dormant?

Yes, mesothelioma can lie dormant for 10-50 years without causing obvious symptoms.

During this time, the asbestos fibers that have been breathed in or swallowed embed themselves in the mesothelial cells that line the lungs and abdomen.

These fibers cause inflammation and cellular damage, which can lead to genetic mutations and the development of cancerous cells over time.

What is the early screening process for mesothelioma?

Early screening for mesothelioma may include a physical exam, imaging tests like X-rays or CT scans, and lung function tests.

While only a biopsy can confirm a mesothelioma diagnosis, these screenings can help detect early signs of the disease.

Jenna TozziWritten by:

Chief Patient Care Advisor

Jenna Tozzi, RN, is the Chief Patient Care Advisor for Mesothelioma Hope. With more than 15 years of experience as an adult and pediatric oncology nurse navigator, Jenna provides exceptional guidance and support to cancer patients and their loved ones. Jenna has been featured in Oncology Nursing News and is a member of the Academy of Oncology Nurse & Patient Navigators & the American Nurses Association.

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References
  1. Centers for Disease Control and Prevention. (n.d.). Latency period. National Cancer Institute. Retrieved July 31, 2024, from https://www.cancer.gov/publications/dictionaries/cancer-terms/def/latency-period
  2. Cohen, S., Reeser, A., & Kozuch, P. (2013). Review of peritoneal mesothelioma. Case Reports in Oncology, 6(2), 363–370. Retrieved July 31, 2024, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790169/
  3. Girard, N. (2022). Mesothelioma management: Recent updates and current challenges. Cancers, 14(18), 4415. Retrieved July 31, 2024, from https://www.mdpi.com/2072-6694/14/18/4415
  4. Kazan-Allen, L. (2017). Asbestos and mesothelioma in India. Asian Pacific Journal of Cancer Prevention, 18(8), 2141–2145. Retrieved July 31, 2024, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292397/
  5. Neumann, V., Loseke, S., Nowak, D., Herth, F., Tannapfel, A., & Kettner, J. (2023). Mesothelioma in Germany 2009–2018: Trends, survival and occupational characteristics. Cancers, 15(24), 5731. Retrieved July 31, 2024, from https://www.mdpi.com/2072-6694/15/24/5731
  6. Tomasson, L., Nordanstig, A., Swartling, P., & Alexandersson, S. (2022). Peritoneal mesothelioma in Sweden: Incidence, diagnosis and survival. Cancer Epidemiology, 77, 102103. Retrieved July 31, 2024, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738972/
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