Dr. Logan Roof

About Dr. Logan Roof

Logan Roof, MD, is a medical oncologist and assistant professor at The Ohio State University, where she cares for patients with mesothelioma and other cancers of the lungs and chest.

Dr. Roof specializes in drug-based cancer treatments, including chemotherapy, immunotherapy, targeted therapy, and clinical trials. She works with patients at every stage of treatment, from newly diagnosed cases to advanced disease and second opinions.

Research is an important part of Dr. Roof’s practice. She studies mesothelioma survival trends, barriers to treatment, and biomarkers that may help guide personalized care. She also contributes to research that expands access to emerging therapies and improves care for patients with thoracic cancers.

Wondering whether Dr. Roof is the right specialist for your care? Our Free Doctor Match can help you connect with mesothelioma experts based on your diagnosis and treatment needs.

What Health Conditions Does Dr. Logan Roof Treat?

Dr. Roof treats cancers that affect the lungs, chest, and surrounding structures. Many of these conditions require ongoing treatment from a team of specialists.

Her areas of expertise include:

• Pleural mesothelioma: An aggressive cancer that develops in the lining around the lungs 10 to 50 years after asbestos exposure
• Lung cancer: Cancer that begins in the lungs and may spread to nearby tissues or other parts of the body
• Metastatic thoracic malignancies: Thoracic cancers that have spread beyond the chest
• Thoracic cancers: A group of cancers affecting the lungs and chest wall
• Thymic cancers: Rare cancers of the thymus, a small gland behind the breastbone

Dr. Roof develops personalized treatment plans based on each patient’s diagnosis, overall health, symptoms, and treatment goals. She also works with surgeons, radiation oncologists, pulmonologists, and other mesothelioma specialists to coordinate care throughout the treatment process.

Dr. Logan Roof’s Approach to Mesothelioma Treatment

No two mesothelioma cases are exactly alike. Dr. Roof develops a personalized mesothelioma treatment plan based on each patient’s diagnosis, overall health, and treatment goals.

Treatment options she may recommend include:

• Chemotherapy: Medications such as cisplatin and pemetrexed that can slow tumor growth and relieve symptoms
• Immunotherapy: Drugs like nivolumab (Opdivo®) and ipilimumab (Yervoy®) that help the immune system recognize and attack cancer cells
• Palliative care: Treatment to manage pain, ease symptoms, and improve quality of life during and after treatment
• Targeted therapy: Medications that target specific changes in cancer cells when appropriate
• Clinical trials: Access to new therapies and treatment combinations that aren’t part of standard care yet

Treatment plans can change over time as new test results become available, the cancer responds to therapy, or new research leads to additional options.

“Every person is different. Every cancer is different. I can’t say that enough, and I think it’s very important that we work as a team of the patient, their loved ones, their family members and caregivers, along with their medical team.”
– Dr. Logan Roof, mesothelioma oncologist

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Dr. Logan Roof’s Medical Background

Dr. Roof earned her medical degree from the Medical University of South Carolina College of Medicine, then completed a Master of Science in Clinical Research at the same school. That research training shaped much of the work she does today on mesothelioma trends and treatment access.

She completed her residency in internal medicine at the University of Cincinnati Medical Center, then a fellowship in hematology and medical oncology at Cleveland Clinic Foundation, where she trained in diagnosing and treating complex cancers.

Today, she continues that work as a medical oncologist and assistant professor at The Ohio State University College of Medicine.

Work Experience

Dr. Roof has devoted her career to advancing care for patients with thoracic cancers through both clinical practice and research.

Her experience includes:

• Medical oncologist at The Ohio State University Comprehensive Cancer Center
• Assistant professor at The Ohio State University College of Medicine
• Clinical researcher focused on mesothelioma and lung cancer
• Investigator in thoracic oncology clinical trials
• Contributor to national oncology treatment guidelines

Her work spans direct patient care, cancer research, and efforts to improve access to high-quality treatment.

Highlights of Dr. Logan Roof’s Medical Career

Dr. Roof has built a reputation for combining evidence-based cancer treatment with research aimed at closing gaps in mesothelioma and lung cancer care. She contributes to national treatment guidelines while continuing to see patients and lead her own research studies.

Awards and Professional Affiliations

Dr. Roof has earned recognition for her research on mesothelioma and lung cancer, and she stays active in several professional groups that shape thoracic cancer care today.

Her honors and affiliations include:

• American Society of Clinical Oncology (ASCO)
• American Society of Hematology (ASH)
• International Association for the Study of Lung Cancer (IASLC)
• Poster Competition selection, Texas Lung Cancer Conference, 2026

She has also contributed to multiple ASCO Living Guidelines, which reflects her standing among cancer researchers and keeps her connected to the latest treatment standards.

Dr. Logan Roof’s Work in Mesothelioma Treatment & Clinical Trials

Clinical trials play an important role in Dr. Roof’s work as both a physician and researcher.

Her research interests include:

• Finding better ways to match mesothelioma patients with the best treatments
• Improving access to specialized therapies and clinical trials
• Expanding the use of immunotherapy drugs for mesothelioma
• Studying survival data to better understand what affects prognosis
• Identifying biomarkers that may help personalize treatment
• Advancing precision oncology to develop more targeted therapies

Through participation in clinical trials and collaborative research efforts, Dr. Roof helps patients gain access to emerging therapies while contributing to future advances in cancer treatment.

Ready to explore your options for treatment and clinical trials? Reach out through our Free Doctor Match to connect with Dr. Roof.

Dr. Logan Roof’s Cancer Research and Published Works

Dr. Roof has written and contributed to numerous publications on mesothelioma and various cancer treatments. Much of her research draws on large national databases to track survival trends and identify gaps in medical care.

Some of her notable studies include:

• Clinical Importance of Molecular Biomarkers in Pleural Mesothelioma. Published in Cancers, February 2026.
• Trends in Pleural Mesothelioma Incidence and Survival in Metropolitan and Nonmetropolitan Areas in the United States. Published in Cancer Medicine, December 2025.
• Therapy for Stage IV Non-Small Cell Lung Cancer With Driver Alterations: ASCO Living Guideline, Version 2025.1. Published in Journal of Clinical Oncology, July 2025.
• Trends in Mesothelioma Mortality in the United States Between 1999 and 2020. Published in JTO Clinical and Research Reports, February 2025.

This research has helped track how mesothelioma and lung cancer affect different populations, and how new therapies are improving life expectancy for both of these asbestos-related diseases.

Get Connected With Dr. Logan Roof for Treatment

Choosing a mesothelioma specialist takes more than comparing credentials. You want a doctor with experience treating this rare cancer, access to the latest therapies, and a care team that understands your needs.

Logan Roof, MD, provides mesothelioma patients in Ohio with chemotherapy, immunotherapy, targeted therapy, and access to clinical trials. She also studies new ways to improve mesothelioma treatment, bringing the latest research into her practice.

If you’d like help finding a mesothelioma specialist, we’re here to help. Mesothelioma Hope connects patients and families with experienced doctors across the country.

Call (866) 608-8933 or start your Free Doctor Match to explore your options.